Recurrent granulomatous mastitis associated with breast sparganosis: a case report
Issued Date
2026-01-01
Resource Type
ISSN
12019712
eISSN
18783511
Scopus ID
2-s2.0-105023889879
Pubmed ID
41242689
Journal Title
International Journal of Infectious Diseases
Volume
162
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Infectious Diseases Vol.162 (2026)
Suggested Citation
Promkrabin W., Sithinamsuwan P., Warnnissorn M., Sarasombath P.T., Apiwat W., Pisarnturakit P., Wangchinda W. Recurrent granulomatous mastitis associated with breast sparganosis: a case report. International Journal of Infectious Diseases Vol.162 (2026). doi:10.1016/j.ijid.2025.108214 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/114414
Title
Recurrent granulomatous mastitis associated with breast sparganosis: a case report
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Background Granulomatous mastitis is an uncommon chronic inflammatory breast disease with diverse etiologies, including infectious causes. Case Description Here, we report the case of a 74-year-old Thai woman with recurrent breast mastitis due to rare breast sparganosis. Four years after an initial diagnosis of granulomatous mastitis of unknown etiology, she presented with a new painless breast mass at a different site. Histopathological examination of a new lesion revealed a cestode worm surrounded by reactive lymphoid hyperplasia. Molecular identification using PCR targeting Cytochrome Oxidase subunit I (COI) gene highly suggested the causative species as Spirometra mansoni and retrospective PCR of the initial breast lesion was also positive for the same species. The patient underwent surgical excision followed by praziquantel therapy, without recurrence at 12-months of follow-up. Conclusion This case underscores the need to consider parasitic infection as a cause of granulomatous mastitis in endemic regions and highlights the value of molecular diagnostics when histopathology is inconclusive. Complete surgical excision remains the cornerstone of treatment, making an accurate diagnosis essential, as management differs from other forms of granulomatous mastitis.