Multifunctional strontium-MOFs-based dental adhesive: Innovation for enhanced bonding performance and bioactivity
Issued Date
2026-01-01
Resource Type
ISSN
01437496
Scopus ID
2-s2.0-105020266343
Journal Title
International Journal of Adhesion and Adhesives
Volume
144
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Adhesion and Adhesives Vol.144 (2026)
Suggested Citation
Matphang S., Aueboonprasert N., Rattanakam R., Teanchai C., Sinthuvanich C., Attarataya J., Sonthisathaporn M., Akkarachaneeyakorn K. Multifunctional strontium-MOFs-based dental adhesive: Innovation for enhanced bonding performance and bioactivity. International Journal of Adhesion and Adhesives Vol.144 (2026). doi:10.1016/j.ijadhadh.2025.104189 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/114469
Title
Multifunctional strontium-MOFs-based dental adhesive: Innovation for enhanced bonding performance and bioactivity
Corresponding Author(s)
Other Contributor(s)
Abstract
Dental adhesives are primarily designed for durable adhesion between restorative materials and tooth structures. In addition to their bonding function, formulations increasingly incorporate bioactive fillers that promote remineralization, prevent secondary caries, and prolong the longevity of restorations. In this in vitro study, a novel bioactive dental adhesive was developed using strontium-based metal-organic frameworks (Sr-MOFs) with fumarate ligands as functional nanofillers. The incorporation of 0.5 wt% Sr-MOFs significantly improved the micro-tensile bond strength to 27.04 ± 6.53 MPa (p < 0.05) compared to the control, while maintaining its performance after 6 months of aging. Nanoleakage assessments confirmed superior sealing and reduced silver nitrate penetration, attributed to the nano-sized Sr-MOFs and chemical interaction between the fumarate's carboxylate groups and calcium in dentin. The adhesive also demonstrated remineralization capabilities through the deposition of apatite-like minerals when immersed in SBF. Additionally, non-cytotoxic behavior was observed, with cell viability exceeding 70 % under ISO 10993 guidelines. These findings highlight Sr-MOFs with fumarate as a promising filler for dental adhesives, supporting durable bonding and mineral regeneration for long-term restoration success. Further in vivo validation is required to demonstrate the clinical significance and practical application of these findings.