Postoperative Radiotherapy in Spinal Rosai-Dorfman Disease: A Case Report and Literature Review
Issued Date
2026-01-01
Resource Type
eISSN
16626575
Scopus ID
2-s2.0-105028455711
Journal Title
Case Reports in Oncology
Start Page
9
End Page
16
Rights Holder(s)
SCOPUS
Bibliographic Citation
Case Reports in Oncology (2026) , 9-16
Suggested Citation
Thaweerat W., Dankulchai P., Muangsomboon S. Postoperative Radiotherapy in Spinal Rosai-Dorfman Disease: A Case Report and Literature Review. Case Reports in Oncology (2026) , 9-16. 16. doi:10.1159/000549467 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/114518
Title
Postoperative Radiotherapy in Spinal Rosai-Dorfman Disease: A Case Report and Literature Review
Author(s)
Author's Affiliation
Corresponding Author(s)
Other Contributor(s)
Abstract
Abstract – Introduction: Rosai-Dorfman disease (RDD) is a rare non-Langerhans cell histiocytosis with no well-established treatment approaches. Surgery is typically indicated for symptomatic patients, but adjuvant treatment to reduce recurrence is infrequently addressed in the literature. Case Presentation: Herein, we describe the case of a 77-year-old woman with a neurological deficit and an infiltrative epidural soft tissue mass at the T3 to T9 levels, as revealed by magnetic resonance imaging (MRI). Following complete tumor resection, pathological examination confirmed spinal RDD. The patient subsequently received postoperative radiotherapy with a dose of 30 Gy in 15 fractions 4 weeks later. At the 18-month postoperative follow-up, the patient was clinically improved and her MRI at 1 year showed no recurrence. Conclusions: Postoperative radiotherapy in spinal RDD remains controversial due to insufficient clinical evidence. Nevertheless, few case reports did not show treatment-related complications.