Publication: Dihydronaphthalenones from endophytic fungus Fusarium sp. BCC14842
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Issued Date
2011-09-30
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ISSN
14645416
00404020
00404020
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2-s2.0-80052021231
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Mahidol University
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SCOPUS
Bibliographic Citation
Tetrahedron. Vol.67, No.39 (2011), 7540-7547
Suggested Citation
Jittra Kornsakulkarn, Kulvadee Dolsophon, Nattawut Boonyuen, Tanapong Boonruangprapa, Pranee Rachtawee, Samran Prabpai, Palangpon Kongsaeree, Chawanee Thongpanchang Dihydronaphthalenones from endophytic fungus Fusarium sp. BCC14842. Tetrahedron. Vol.67, No.39 (2011), 7540-7547. doi:10.1016/j.tet.2011.07.078 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/11467
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Title
Dihydronaphthalenones from endophytic fungus Fusarium sp. BCC14842
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Abstract
Eleven new dihydronaphthalenones 1-11, together with five known compounds; 5-hydroxydihydrofusarubin C (12), javanicin, bostr ycoidin, anhydrofusarubin, and 3-O-methylfusarubin, were isolated from the endophytic fungus Fusarium sp. BCC14842. Structures were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. Javanicin, 3-O-methylfusarubin, compounds 3 and 7 exhibited antimycobacterial and cytotoxic activities. Javanicin also displayed antifungal activity with IC 50 of 6.16 μg/mL, while compounds 2, 4, 5, 8, and 12 showed only cytotoxic activity. © 2011 Elsevier Ltd. All rights reserved.