Chronic Malaria Is Associated With Trauma-related Splenic Rupture Requiring Splenectomy
Issued Date
2026-03-15
Resource Type
ISSN
00221899
eISSN
15376613
Scopus ID
2-s2.0-105033106091
Pubmed ID
41378825
Journal Title
Journal of Infectious Diseases
Volume
233
Issue
3
Start Page
e740
End Page
e744
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Infectious Diseases Vol.233 No.3 (2026) , e740-e744
Suggested Citation
Shanti P.A.I., Alexander K., Candrawati F., Andries B., Kambuaya N.N., Rini H., Amelia A.R., Puspitasari A.M., Amalia R., Rahmayenti D.A., Leonardo L., Prayoga P., Trianty L., Pava Z., Kenangalem E., Auburn S., Price R.N., Laksanawati I.S., Buffet P.A., Noviyanti R., Anstey N.M., Poespoprodjo J.R., Kho S. Chronic Malaria Is Associated With Trauma-related Splenic Rupture Requiring Splenectomy. Journal of Infectious Diseases Vol.233 No.3 (2026) , e740-e744. e744. doi:10.1093/infdis/jiaf629 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/115876
Title
Chronic Malaria Is Associated With Trauma-related Splenic Rupture Requiring Splenectomy
Corresponding Author(s)
Other Contributor(s)
Abstract
Splenic rupture is a recognized complication of acute Plasmodium falciparum and Plasmodium vivax malaria, but the risk of splenic rupture in chronic asymptomatic infections is unknown. In Timika, Papua, Indonesia, we determined the proportion of PCR-detectable asymptomatic peripheral parasitemia in patients undergoing trauma-related splenectomy (2015–21) and found it was more than twice the proportion compared to a 2013 household survey of the general population (87.9% [29/33] vs 38.6% [697/1807]; P <.0001). Our findings suggest asymptomatic parasitemia with either P. falciparum or P. vivax is associated with splenic rupture following trauma, pointing toward an additional consequence of chronic infection in malaria-endemic areas.