A Clinically-Oriented Antimicrobial Resistance Surveillance Network 2 (ACORN2): Results from three hospitals in Vietnam
Issued Date
2026-07-01
Resource Type
ISSN
12019712
eISSN
18783511
Scopus ID
2-s2.0-105038003267
Pubmed ID
41932572
Journal Title
International Journal of Infectious Diseases
Volume
168
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Infectious Diseases Vol.168 (2026)
Suggested Citation
Thi H.N., Phuong N.Q., Thach P.N., Van Giang T., Huong H.T.L., Tung T.H., Trang V.D., Van Bac T., Ngoc N.T., Giang L.H., Thanh D.D., Khiem D.P., Hai D.T., Trang H.T., Dung P.T., Ha N.T., Van Tuan M., Nguyen T.D., Tran V.B., Thi H.T.T., Thi T.L., Thi P.P., Hoang V.L., Thi B.O.N., Thi D.D.N., Nguyen T.D., Nguyen X.H., Thi H.N., Le Q.T.P., Tran Q.N., Tran D.H., Duong T.D., Thi Y.L.N., Ngoc N.M., Nguyen H.D., Thi Q.A.N., Thi K.N.N., Thi K.A.N., Thi D.T.N., Thi D.L.P., Thi M.T.H., Thi N.N., Thi H.P.T., Thi H.H.L., Nguyen T.T., Cao M.U.N., Le N.A., Thi B.K.T., Ho K.G., Thi L.P.N., Bui T.T., Thi T.T.N., Dung V.T.V., Wannapinij P., Chamsukhee V., Waithira N., Roberts T., Ling C.L., Hopkins J., Turner P., van Doorn H.R. A Clinically-Oriented Antimicrobial Resistance Surveillance Network 2 (ACORN2): Results from three hospitals in Vietnam. International Journal of Infectious Diseases Vol.168 (2026). doi:10.1016/j.ijid.2026.108673 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/116739
Title
A Clinically-Oriented Antimicrobial Resistance Surveillance Network 2 (ACORN2): Results from three hospitals in Vietnam
Author(s)
Thi H.N.
Phuong N.Q.
Thach P.N.
Van Giang T.
Huong H.T.L.
Tung T.H.
Trang V.D.
Van Bac T.
Ngoc N.T.
Giang L.H.
Thanh D.D.
Khiem D.P.
Hai D.T.
Trang H.T.
Dung P.T.
Ha N.T.
Van Tuan M.
Nguyen T.D.
Tran V.B.
Thi H.T.T.
Thi T.L.
Thi P.P.
Hoang V.L.
Thi B.O.N.
Thi D.D.N.
Nguyen T.D.
Nguyen X.H.
Thi H.N.
Le Q.T.P.
Tran Q.N.
Tran D.H.
Duong T.D.
Thi Y.L.N.
Ngoc N.M.
Nguyen H.D.
Thi Q.A.N.
Thi K.N.N.
Thi K.A.N.
Thi D.T.N.
Thi D.L.P.
Thi M.T.H.
Thi N.N.
Thi H.P.T.
Thi H.H.L.
Nguyen T.T.
Cao M.U.N.
Le N.A.
Thi B.K.T.
Ho K.G.
Thi L.P.N.
Bui T.T.
Thi T.T.N.
Dung V.T.V.
Wannapinij P.
Chamsukhee V.
Waithira N.
Roberts T.
Ling C.L.
Hopkins J.
Turner P.
van Doorn H.R.
Phuong N.Q.
Thach P.N.
Van Giang T.
Huong H.T.L.
Tung T.H.
Trang V.D.
Van Bac T.
Ngoc N.T.
Giang L.H.
Thanh D.D.
Khiem D.P.
Hai D.T.
Trang H.T.
Dung P.T.
Ha N.T.
Van Tuan M.
Nguyen T.D.
Tran V.B.
Thi H.T.T.
Thi T.L.
Thi P.P.
Hoang V.L.
Thi B.O.N.
Thi D.D.N.
Nguyen T.D.
Nguyen X.H.
Thi H.N.
Le Q.T.P.
Tran Q.N.
Tran D.H.
Duong T.D.
Thi Y.L.N.
Ngoc N.M.
Nguyen H.D.
Thi Q.A.N.
Thi K.N.N.
Thi K.A.N.
Thi D.T.N.
Thi D.L.P.
Thi M.T.H.
Thi N.N.
Thi H.P.T.
Thi H.H.L.
Nguyen T.T.
Cao M.U.N.
Le N.A.
Thi B.K.T.
Ho K.G.
Thi L.P.N.
Bui T.T.
Thi T.T.N.
Dung V.T.V.
Wannapinij P.
Chamsukhee V.
Waithira N.
Roberts T.
Ling C.L.
Hopkins J.
Turner P.
van Doorn H.R.
Author's Affiliation
Nuffield Department of Medicine
Mahidol Oxford Tropical Medicine Research Unit
Oxford University Clinical Research Unit
Mahosot Hospital, Lao
Angkor Hospital for Children
National Hospital for Tropical Diseases
Ha Noi Medical University
National Lung Hospital
Children's Hospital 2
Hue Central Hospital
Mahidol Oxford Tropical Medicine Research Unit
Oxford University Clinical Research Unit
Mahosot Hospital, Lao
Angkor Hospital for Children
National Hospital for Tropical Diseases
Ha Noi Medical University
National Lung Hospital
Children's Hospital 2
Hue Central Hospital
Corresponding Author(s)
Other Contributor(s)
Abstract
Objectives ACORN (A Clinically-Oriented Antimicrobial Resistance Surveillance Network) integrates antimicrobial resistance (AMR) surveillance with clinical data in hospitals across low- and middle-income countries. We describe ACORN2 data from Vietnam and compare findings with existing national surveillance data. Methods Hospitalized patients receiving intravenous antibiotics were enrolled from selected wards in three national hospitals. Infections were classified as community-acquired (CAI), healthcare-associated (HCAI), or hospital-acquired (HAI). Microbiological data were deduplicated to the first isolate of each bacterial species per sample types within each infection episode. Pathogen distribution and resistance patterns were analyzed by hospital, infection origin, and sample type. Results Among 5449 infection episodes, 2817 were CAI, 1615 HCAI, and 1017 HAI. Escherichia coli and Staphylococcus aureus predominated in sterile samples, while Pseudomonas aeruginosa, Acinetobacter baumannii , and Klebsiella pneumoniae were most frequent in non-sterile samples. A. baumannii and P. aeruginosa were common in HCAI and HAI. Resistance to third-generation cephalosporins and carbapenems was markedly higher in HCAI and HAI than CAI, with widespread carbapenem resistance in A. baumannii . Overall AMR levels exceeded those reported in previous national surveillance data. Conclusion ACORN2 demonstrates a high burden of AMR in Vietnam, particularly in healthcare- and hospital-acquired infections, underscoring the value of clinically oriented surveillance to inform treatment and stewardship policies.