Correction : Human adipose stem cell-derived exosomes modulate the transcriptome of D-galactose-induced neuronal cells (Scientific Reports, (2026), 16, 1, (4575), 10.1038/s41598-025-34661-5)
Issued Date
2026-12-01
Resource Type
eISSN
20452322
Scopus ID
2-s2.0-105042294580
Journal Title
Scientific Reports
Volume
16
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
Scientific Reports Vol.16 No.1 (2026)
Suggested Citation
Khongkla E., Promtap K., Meerasri J., Mo-Mai P., Chankamngoen W., Sirinonthanawech N., Chetsawang B. Correction : Human adipose stem cell-derived exosomes modulate the transcriptome of D-galactose-induced neuronal cells (Scientific Reports, (2026), 16, 1, (4575), 10.1038/s41598-025-34661-5). Scientific Reports Vol.16 No.1 (2026). doi:10.1038/s41598-026-57774-x Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/117520
Title
Correction : Human adipose stem cell-derived exosomes modulate the transcriptome of D-galactose-induced neuronal cells (Scientific Reports, (2026), 16, 1, (4575), 10.1038/s41598-025-34661-5)
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Abstract
Correction to: Scientific Reportshttps://doi.org/10.1038/s41598-025-34661-5, published online 04 January 2026 The original version of this Article contained errors. The title has been corrected and now reads: “Human adipose stem cell-derived exosomes modulate the transcriptome of d-galactose-induced neuronal cells”. Furthermore, in the Abstract, the term ‘PKH26’ was incorrectly stated as ‘PHK26’. Lastly, several instances of in-text References to Figures in the Results section of the main Article text were incorrect. As a result, under the subheading ‘Uptake of hASC-exosomes by neuronal CAD cells’, “3D visualization was performed to confirm that the exosomes were internalized within the cytosol rather than remaining attached to the cell membrane (Fig. 2a and Supplementary File 1).” now reads: “3D visualization was performed to confirm that the exosomes were internalized within the cytosol rather than remaining attached to the cell membrane (Fig. 2c and Supplementary File 1).” Under the subheading ‘Illumina-based mRNA sequencing analysis identified 3019 genes that were differentially expressed in the presence of hASC-exosomes in DG-neuronal cells’, “Together with the heatmap hierarchical clustering presented in Fig. 4c,d, the results revealed a clear distinction between comparative groups on the basis of the abundance profile of DEGs.” now reads: “Together with the heatmap hierarchical clustering presented in Fig. 5c,d, the results revealed a clear distinction between comparative groups on the basis of the abundance profile of DEGs.” Under the same subheading, “On the basis of the results of the GO enrichment analysis, the biological process associated with the DG-treated cells that was most significantly enriched was the cellular response to DNA damage stimulus, in which the H2AX gene was enriched (Fig. 5a,b).” now reads: “On the basis of the results of the GO enrichment analysis, the biological process associated with the DG-treated cells that was most significantly enriched was the cellular response to DNA damage stimulus, in which the H2AX gene was enriched (Fig. 6a,b).” And, “As shown in Fig. 6, the protein–protein interaction (PPI) network of the DEGs revealed a large cluster centered around mitogen-activated protein kinase 13 (MAPK13), also known as stress-activated protein kinase 4 (SAPK4).” now reads: “As shown in Fig. 7, the protein–protein interaction (PPI) network of the DEGs revealed a large cluster centered around mitogen-activated protein kinase 13 (MAPK13), also known as stress-activated protein kinase 4 (SAPK4).” Under the subheading ‘hASC-exosomes induced the upregulation of genes associated with metabolic processes, DNA replication, and neuronal signal transduction but suppressed global translation in the DG-treated model’, “In the comparison of B vs. C, the upregulated DEGs were enriched in several metabolic and neuronal processes, including cholesterol biosynthetic processes, oxidative phosphorylation, regulation of cell junction assembly, receptor internalization, neuronal signal transduction, mitochondria–nucleus signaling, calcium ion transport, synapse organization, the cellular response to potassium ions, and negative regulation of axon regeneration, as well as pathways related to DNA replication and regulation of cell cycle arrest (Fig. 7a).” now reads: “In the comparison of B vs. C, the upregulated DEGs were enriched in several metabolic and neuronal processes, including cholesterol biosynthetic processes, oxidative phosphorylation, regulation of cell junction assembly, receptor internalization, neuronal signal transduction, mitochondria–nucleus signaling, calcium ion transport, synapse organization, the cellular response to potassium ions, and negative regulation of axon regeneration, as well as pathways related to DNA replication and regulation of cell cycle arrest (Fig. 8a).” And, “Furthermore, genes involved in the DNA replication complex, factor C complex, histone deacetylase complex, and CD40 receptor complex were also upregulated in the presence of hASC-exosomes (Fig. 7b,c).” now reads: “Furthermore, genes involved in the DNA replication complex, factor C complex, histone deacetylase complex, and CD40 receptor complex were also upregulated in the presence of hASC-exosomes (Fig. 8b,c).” Under the subheading ‘A number of genes involved in inflammatory responses are regulated by hASC-exosomes’, “GO enrichment analysis was performed to identify the top biological processes that may underlie the set of downregulated genes (Fig. 8).” now reads: “GO enrichment analysis was performed to identify the top biological processes that may underlie the set of downregulated genes (Fig. 9).” And, “The transcriptomic expression (FPKM) values of the genes involved in the inflammatory response are plotted in Fig. 9.” now reads: “The transcriptomic expression (FPKM) values of the genes involved in the inflammatory response are plotted in Fig. 10.” And finally, under the subheading ‘Genes associated with aging and neurodegeneration are suppressed by hASC-exosomes, “The expression levels of genes associated with apoptosis and cellular senescence across the experimental groups are presented in Fig. 10.” now reads: “The expression levels of genes associated with apoptosis and cellular senescence across the experimental groups are presented in Fig. 11.” The original Article has been corrected.