Publication:
Restriction endonuclease analysis of deoxyribonucleic acid (Dna) from genital herpes simplex virus type 2 isolates in thailand

Issued Date

1990-01-01

Resource Type

Article

ISSN

15374521
01485717

Other identifier(s)

2-s2.0-0025266012

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Sexually Transmitted Diseases. Vol.17, No.1 (1990), 42-47

Suggested Citation

Wasun Chantrattta, Chalobon Yoosook Restriction endonuclease analysis of deoxyribonucleic acid (Dna) from genital herpes simplex virus type 2 isolates in thailand. Sexually Transmitted Diseases. Vol.17, No.1 (1990), 42-47. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/16097

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Title

Restriction endonuclease analysis of deoxyribonucleic acid (Dna) from genital herpes simplex virus type 2 isolates in thailand

Author(s)

Wasun Chantrattta
 Chalobon Yoosook

Other Contributor(s)

Mahidol University

Abstract

Local herpes simplex virus (HSV) isolates were characterized by the use of BamHI, KpnI, and EcoRI restriction endonucleases. Analysis of 120 clinical isolates by observation of presence or absence of cleavage sites and of mobility variation in deoxyribonucleic acid (DNA) fragments from the terminal and joint regions of the HSV genome revealed that 112 (93.3%) were type-2 (HSV-2) and the others were type-l (HSV-1), mixed HSV-2 and HSV-I, and mixed HSV-2 strains. The genomes of HSV-2 isolates were highly conserved and could be classified into 25 distinct restriction endonuclease (RE) cleavage patterns, which differed from those obtained with isolates of other countries. © 1990 American Sexually Transmitted Diseases Association.

Keyword(s)

Medicine

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URI

https://repository.li.mahidol.ac.th/handle/123456789/16097

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Scopus 1969-1990