Publication:
Strategies for the prevention of antimalarial drug resistance: Rationale for combination chemotherapy for malaria

1

Issued Date

1996-01-01

Resource Type

Review

ISSN

01694758

DOI

10.1016/0169-4758(96)10055-7

Other identifier(s)

2-s2.0-0030271322

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Parasitology Today. Vol.12, No.10 (1996), 399-401

Suggested Citation

Nick J. White, Piero L. Olliaro Strategies for the prevention of antimalarial drug resistance: Rationale for combination chemotherapy for malaria. Parasitology Today. Vol.12, No.10 (1996), 399-401. doi:10.1016/0169-4758(96)10055-7 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17624

Research Projects

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Thesis

Title

Strategies for the prevention of antimalarial drug resistance: Rationale for combination chemotherapy for malaria

Author(s)

Nick J. White
 Piero L. Olliaro

Other Contributor(s)

Mahidol University
 Cho Quan Hospital
 Organisation Mondiale de la Sante

Abstract

Among the several 'tropical' diseases that affect humans, malaria poses special control problems due to the increasing population at risk from the disease, the difficulties in eradicating the mosquito vector in the tropics and the emergence and spread of parasite resistance to commonly used antimalarial drugs. There is both clinical experience and experimental evidence that, however effective when first introduced, the lifespan of drugs is inevitably curtailed by the emergence of resistant parasites. Resistance is the most important factor in determining the useful lifespan of antimalarial drugs. In this review, Nick White and Piero Olliaro discuss the rationale for combination chemotherapy.

Keyword(s)

Immunology and Microbiology

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/17624

Collections

Scopus 1991-2000