Publication: Remission of recurrent cervical cancer with paclitaxel and carboplatin: A case report and review of literature
Issued Date
1996-12-21
Resource Type
ISSN
03922936
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2-s2.0-0029827414
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Mahidol University
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SCOPUS
Bibliographic Citation
European Journal of Gynaecological Oncology. Vol.17, No.6 (1996), 493-496
Suggested Citation
W. Termrungruanglert, A. P. Kudelka, S. Piamsomboon, C. L. Edwards, C. F. Verschraegen, E. Loyer, J. J. Kavanagh Remission of recurrent cervical cancer with paclitaxel and carboplatin: A case report and review of literature. European Journal of Gynaecological Oncology. Vol.17, No.6 (1996), 493-496. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17649
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Title
Remission of recurrent cervical cancer with paclitaxel and carboplatin: A case report and review of literature
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Abstract
We report the case of a patient with recurrent squamous cell carcinoma of the cervix, that metastasized to the paraaortic and supraclavicular lymph nodes and the lungs after primary radiotherapy for stage IIB. The tumor was refractory to multiple drug regimens. A combination of paclitaxel (135 mg/m2intravenous infusion over 24) hours and carboplatin with a target area under the curve of 7.5 mg.min/mL were then administered and repeated every 4 weeks. The patient tolerated the chemotherapy well with myeloprotection from granulocyte colony-stimulating factor and the disease went into remission. Thus, the combination of paclitaxel and car boplatin may have antirumor activity in advanced or recurrent squamous cell carcinoma of the cervix.