Publication: Causes of chronic diarrhea in patients with AIDS in Thailand: A prospective clinical and microbiological study
2
Issued Date
1996-01-01
Resource Type
ISSN
09441174
Other identifier(s)
2-s2.0-0029802569
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Gastroenterology. Vol.31, No.4 (1996), 533-537
Suggested Citation
Sathaporn Manatsathit Causes of chronic diarrhea in patients with AIDS in Thailand: A prospective clinical and microbiological study. Journal of Gastroenterology. Vol.31, No.4 (1996), 533-537. doi:10.1007/BF02355053 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17805
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Title
Causes of chronic diarrhea in patients with AIDS in Thailand: A prospective clinical and microbiological study
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Abstract
A prospective study was designed to investigate the causes of chronic diarrhea in AIDS patients in Thailand. Forty-five patients from Bamrasnaradura Infectious Diseases Hospital were enrolled. Extensive investigations included multiple stool examinations for ova and parasites, using the stool formalin-ether concentration method, stool culture, stool acid-fast bacilli (AFB) stain, stool modified AFB stain, esophagogastroduoscopy with duodenal aspirate and biopsy, and colonoscopy with biopsy. Biopsied specimens were examined with H and E, Giemsa, Gram, Periodic acid Schiff, and AFB stains. Definitive causes were found in 29 patients (64.4%). Of these 29, 7 patients were found to habor more than 1 pathogen (15.5%). The most commonly found enteric pathogen was Cryptosporidium parvum (20.0%). Less frequently found pathogens were Mycobacterium tuberculosis (17.8%), Salmonella spp. (15.5%), Cytomegalovirus (11.1%), Mycobacterium avium intracellulare (6.6%), Strongyloides stercoralis (4.4%), Giardia lamblia (4.4%), Cryptococcus neoformans (2.2%), Histoplasma capsulatum (2.2%), Campylobacter jejun (2.2%), and Cyclospora cayetanensis (2.2%). Salmonella spp., Mycobacterium tuberculosis, and Mycobacterium avium intracellulare infections were shown to be more common in Thailand than in African countries.