Publication: Precursor-directed biosynthesis of beauvericin analogs by the insect pathogenic fungus Paecilomyces tenuipes BCC 1614
Issued Date
2002-04-22
Resource Type
ISSN
00404020
Other identifier(s)
2-s2.0-0037156526
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Tetrahedron. Vol.58, No.17 (2002), 3355-3360
Suggested Citation
Chongdee Nilanonta, Masahiko Isaka, Prasat Kittakoop, Srisuda Trakulnaleamsai, Morakot Tanticharoen, Yodhathai Thebtaranonth Precursor-directed biosynthesis of beauvericin analogs by the insect pathogenic fungus Paecilomyces tenuipes BCC 1614. Tetrahedron. Vol.58, No.17 (2002), 3355-3360. doi:10.1016/S0040-4020(02)00294-6 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/20068
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Precursor-directed biosynthesis of beauvericin analogs by the insect pathogenic fungus Paecilomyces tenuipes BCC 1614
Other Contributor(s)
Abstract
Precursor-directed biosynthesis of beauvericin analogs, cyclohexadepsipeptide antibiotics, was investigated using the insect pathogenic fungus Paecilomyces tenuipes BCC 1614. Feeding L-isoleucine or D-alloisoleucine in liquid medium led to the enhanced production of beauvericin A and beauvericin B together with beauvericin and a missing analog, beauvericin C. Feeding experiments with D-isoleucine or L-alloisoleucine resulted in the production of diastereomers of beauvericins A, B and C, named allobeauvericins A, B and C, respectively. © 2002 Elsevier Science Ltd. All rights reserved.