Publication: Mycobacterium Tuberculosis infection among HIV/AIDS patients in Thailand: Clinical manifestations and outcomes
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Issued Date
2002-12-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0036598547
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 346-351
Suggested Citation
Nimfa M. Putong, Punnee Pitisuttithum, Wichai Supanaranond, Benjaluck Phonrat, Somsit Tansuphasawadikul, Udomsak Silachamroon, Huot Chan Yuda, Valai Bussaratid, Nalinee Aswapokee Mycobacterium Tuberculosis infection among HIV/AIDS patients in Thailand: Clinical manifestations and outcomes. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.33, No.2 (2002), 346-351. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/20282
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Title
Mycobacterium Tuberculosis infection among HIV/AIDS patients in Thailand: Clinical manifestations and outcomes
Abstract
A one year retrospective study, was conducted at Bamrasnaradura Hospital, Nonthaburi Province, Bangkok, Thailand, of 271 subjects with both TB and HIV/AIDS. Single males (median age group 31 to 40 years) were most likely to develop co-infection. The commonest clinical manifestations on initial presentation included a low grade fever, cough, weight loss, lymphadenopathy with pancytopenia, and lung infiltrates. Multi-drug resistant TB (MDR-TB) was found in 26.6% of the subjects which was significantly associated with a past history of anti-TB treatment (p = 0.005; OR=2.5); it was also significantly associated with disseminated TB (p = 0.022; OR=1.9) and mortality (p= 0.013; OR=2.8). Analysis of clinical outcomes showed that 46.7% were lost to follow-up and 13.3% had died by the time of follow-up. Among those who survived, only 11.4% had been successfully treated; the rest had not improved due to relapse (2.9%), therapeutic failure (8.8%), treatment in progress (5.9%), and failure to complete treatment (10.7%).