Publication: Cytotoxic Coumarins from Mammea harmandii
1
Issued Date
2003-11-01
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ISSN
00320943
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2-s2.0-0347950974
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Mahidol University
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SCOPUS
Bibliographic Citation
Planta Medica. Vol.69, No.11 (2003), 1048-1051
Suggested Citation
Vichai Reutrakul, Pornsiri Leewanich, Patoomratana Tuchinda, Manat Pohmakotr, Thaworn Jaipetch, Samaisukh Sophasan, Thawatchai Santisuk Cytotoxic Coumarins from Mammea harmandii. Planta Medica. Vol.69, No.11 (2003), 1048-1051. doi:10.1055/s-2003-45154 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/20681
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Title
Cytotoxic Coumarins from Mammea harmandii
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Abstract
Two new naturally occurring coumarins, isomesuol (1) and mammearin A (2), together with nine known Mammea coumarins 3-11 were isolated from the EtOAc extract of the leaves and twigs of Mammea harmandii. Coumarins 1, 3 and 4 showed cytotoxicity against a panel of mammalian cancer cell lines. Their structures were determined by spectroscopic methods. The assignments of13C-NMR signals of isomesuol (1), which was isolated for the first time as a natural product, have been revised.