Publication: Effects of an iron supplementation trial on the Fe status of Thai schoolchildren
1
Issued Date
1992-01-01
Resource Type
ISSN
14752662
00071145
00071145
Other identifier(s)
2-s2.0-0026688143
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
British Journal of Nutrition. Vol.68, No.1 (1992), 245-252
Suggested Citation
Phongjan Hathirat, Nittaya J. Kotchabhakdi Effects of an iron supplementation trial on the Fe status of Thai schoolchildren. British Journal of Nutrition. Vol.68, No.1 (1992), 245-252. doi:10.1079/BJN19920081 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/22498
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Title
Effects of an iron supplementation trial on the Fe status of Thai schoolchildren
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Abstract
A double-blind clinical trial was conducted among 9- to 11-year-old children in sixteen schools in the Chon Buri province of Thailand to assess the effects of an iron supplement combined with an anthelminthic agent (i.e. albendazole). In addition to the albendazole, Fe or placebo tablets were distributed to 2268 children enrolled in grades three to five without knowledge of the Fe status of the children. Criteria for case inclusion were: (a) absence of A E Bart's or haemoglobin (Hb) H disease, (b) absence of abnormal Hb EE, and (c) age, 108–144 months. The results showed a significant improvement in the Fe status of the children after 16 weeks of treatment. The increments were: Hb from 124 to 128 g/1, serum ferritin from 34.54 to 104.72 μg/1, transferrin saturation from 24.09 to 35.05%; free erythrocyte protoporphyrin decreased from 444.7 to 281.4 μg/1 erythrocytes. These changes were significantly greater than in the control group that received only the anthelminthic agent. However, the administration of albendazole only also resulted in significant changes in the same Fe indicators. © 1992, The Nutrition Society. All rights reserved.