Publication: Therapy of chronic idiopathic thrombocytopenic purpura in adults: experiences from Thailand.
Issued Date
1993-12-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0027903370
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.24 Suppl 1, (1993), 71-75
Suggested Citation
W. Wanachiwanawin, S. Visudhiphan, A. Pinankijagum, S. Vatanavicharn Therapy of chronic idiopathic thrombocytopenic purpura in adults: experiences from Thailand.. The Southeast Asian journal of tropical medicine and public health. Vol.24 Suppl 1, (1993), 71-75. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/22627
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Title
Therapy of chronic idiopathic thrombocytopenic purpura in adults: experiences from Thailand.
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Abstract
Results of different types of treatment in 416 adults with chronic idiopathic thrombocytopenic purpura (ITP) were analyzed. Of 368 patients treated with corticosteroids, 278 (77%) achieved complete response (CR ie, normalization of platelet count). However, only 18% of patients had continued complete response (CCR). Results of splenectomy was analyzed in 126 patients, 49% of them achieved CCR and 76% of them had beneficial effects from the operation. Emergency splenectomy was a life saving procedure in 8 of 11 patients with life-threatening hemorrhage. Vinca alkaloids gave a 50% transient CR. Immunosuppressive agents (cyclophosphamide, azathioprine) resulted in only 11% CCR.