Publication:
Prenylated xanthones as potential antiplasmodial substances

2

Issued Date

2006-08-01

Resource Type

Article

ISSN

00320943

DOI

10.1055/s-2006-947190

Other identifier(s)

2-s2.0-33748592259

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Planta Medica. Vol.72, No.10 (2006), 912-916

Suggested Citation

Wilawan Mahabusarakam, Kunnika Kuaha, Prapon Wilairat, Walter C. Taylor Prenylated xanthones as potential antiplasmodial substances. Planta Medica. Vol.72, No.10 (2006), 912-916. doi:10.1055/s-2006-947190 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23002

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Title

Prenylated xanthones as potential antiplasmodial substances

Author(s)

Wilawan Mahabusarakam
 Kunnika Kuaha
 Prapon Wilairat
 Walter C. Taylor

Other Contributor(s)

Prince of Songkla University
 Khon Kaen University
 Mahidol University
 The University of Sydney

Abstract

Mangostin, the major xanthone of Garcinia mangostana, and a series of synthetic derivatives were investigated for their in vitro antiplasmodial activity against Plasmodium falciparum. Mangostin itself showed moderate activity, but prenylated xanthones containing alkylamino functional groups exhibited quite potent antiplasmodial activity. Some structure-activity relationships are proposed. © Georg Thieme Verlag KG Stuttgart.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry
 Medicine
 Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/23002

Collections

Scopus 2006-2010