Cancer Genomics and Proteomics. Vol.3, No.6 (2006), 389-394
Suggested Citation
Pantipa Subhasitanont, Chantragan Srisomsap, Phaibul Punyarit, Jisnuson Svasti Proteomic studies of galectin-3 expression in human thyroid diseases by immunodetection. Cancer Genomics and Proteomics. Vol.3, No.6 (2006), 389-394. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23110
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Proteomic studies of galectin-3 expression in human thyroid diseases by immunodetection
Galectin-3 expression in thyroid diseases was studied by 1-DE immunoblotting. Expression was markedly elevated in thyroid papillary carcinoma, compared to follicular adenoma, follicular carcinoma or non-neoplastic diseases. Galectin-3 expression was also elevated in malignant cancers of bone, breast, colon, esophagus, larynx, lung and ovary. Four cases of thyroid papillary carcinoma with metastasis gave 2-3 bands on 1-DE immunoblotting. 2-DE immunoblotting of gelectin-3 showed 3 dark spots with MW/pI 32.9/8.29, 31.0/8.40 and 30.0/8.40 and 2 light spots.
