Publication: Expression of basement membrane components in odontogenic cysts
Issued Date
2006-05-01
Resource Type
ISSN
16010825
1354523X
1354523X
Other identifier(s)
2-s2.0-33646685012
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Oral Diseases. Vol.12, No.3 (2006), 290-296
Suggested Citation
S. Poomsawat, J. Punyasingh, W. Weerapradist Expression of basement membrane components in odontogenic cysts. Oral Diseases. Vol.12, No.3 (2006), 290-296. doi:10.1111/j.1601-0825.2005.01193.x Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23211
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Expression of basement membrane components in odontogenic cysts
Author(s)
Other Contributor(s)
Abstract
OBJECTIVE: To compare the expression of basement membrane components (BMCs), including laminins 1 and 5, collagen type IV, and fibronectin in odontogenic keratocysts (OKCs) with dentigerous cysts (DCs) and radicular cysts (RCs). MATERIALS AND METHODS: Basement membrane components were analysed in 20 OKCs, 20 DCs and 20 RCs using an immunohistochemical technique. RESULTS: Odontogenic keratocysts, DCs and RCs showed positive reaction to all BMCs studied, with different distributions and intensity. OKCs showed continuous linear deposits for laminins 1 and 5 but two staining patterns (continuous and discontinuous) for collagen type IV and fibronectin. DCs exhibited continuous linear deposits for laminins 1 and 5 and collagen type IV but a discontinuous linear deposit for fibronectin. RCs displayed similar results to DCs for laminin 1, collagen type IV and fibronectin. Laminin 5 in RCs had two staining patterns. Constant results in all cysts were strong intensity for laminin 1 and moderate intensity for laminin 5. CONCLUSIONS: Substantial differences in the expression of BMCs among studied cysts were not observed, suggesting that the separation of the epithelial lining in OKCs is not associated with the existence of these proteins. © 2006 Blackwell Munksgaard All rights reserved.