Publication: Immunological tolerance in allo- and xenografts
Issued Date
2007-12-01
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2-s2.0-84889961337
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Mahidol University
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SCOPUS
Bibliographic Citation
Liver Immunology: Principles and Practice. (2007), 433-449
Suggested Citation
Aftab A. Ansari, Kovit Pattanapanyasat Immunological tolerance in allo- and xenografts. Liver Immunology: Principles and Practice. (2007), 433-449. doi:10.1007/978-1-59745-518-3_34 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/24652
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Title
Immunological tolerance in allo- and xenografts
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Abstract
Advances in surgical techniques and ancillary care, in parallel with advances in clinical immunosuppression, are the reasons for the enormous success that has been achieved to date in solid organ transplantation. Such success has also provided a considerable boost in the advancement of our knowledge of immunological tolerance in allogeneic and (relatively more recently) xenogeneic transplantation. Thus, success in human organ transplantation has provided the incentive and foundation for unraveling some of the mysteries of organ transplant acceptance vs failure and has been the foundation for the science of transplantation immunology, which includes to a large extent studies of the fundamental mechanisms of immunological tolerance and the understanding of the concepts involved in self- vs nonself-discrimination. © 2007 Humana Press Inc.