Publication: Prevalence of disseminated Mycobacterium avium complex infection in thai AIDS patients
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1999-07-01
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01252208
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2-s2.0-0033162536
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Mahidol University
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Journal of the Medical Association of Thailand. Vol.82, No.7 (1999), 643-647
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Charoen Chuchottaworn, Boonmee Sathapatayawongs, Somsit Tansuphsawadikul, Surapol Suwanagool, Pacharee Kantipong, Sopa Pornchaipoonthavee (1999). Prevalence of disseminated Mycobacterium avium complex infection in thai AIDS patients. Retrieved from: https://hdl.handle.net/20.500.14594/25624.
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Prevalence of disseminated Mycobacterium avium complex infection in thai AIDS patients
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Abstract
Infections caused by nontuberculous mycobacteria (NTM), although rare in immuno-competent individuals, can potentially produce problems in immunocompromised patients such as those with acquired immunodeficiency syndrome (AIDS). In this study, hemocultures for mycobacteria using radiometric BACTEC 13A media were taken from 334 patients with known human immunodeficiency virus infection admitted to four referral hospitals with fever of unknown site of infection and negative blood cultures for pathogenic bacteria. The mycobacterial hemocultures were positive for Mycobacterium avium complex (MAC) in 58 patients (17.4%) and positive for Mycobacterium tuberculosis in 34 patients (10.2%). The results of this study have proved that MAC infection, indeed, exists among Thai AIDS patients. The prevalence of MAC infection in Thailand is very high and comparable to that in the western countries. Physicians taking care of AIDS patients in Thailand should be aware of potential MAC infection, particularly in advanced cases. Considering the high prevalence of infection, primary prophylaxis against MAC infection in advanced AIDS patients is recommended.