Publication: Hepatoprotective potential of extracts from seeds of Areca catechu and nutgalls of Quercus infectoria
1
Issued Date
2009-01-01
Resource Type
ISSN
14203049
Other identifier(s)
2-s2.0-73849143161
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Molecules. Vol.14, No.12 (2009), 4987-5000
Suggested Citation
Pimolpan Pithayanukul, Saruth Nithitanakool, Rapepol Bavovada Hepatoprotective potential of extracts from seeds of Areca catechu and nutgalls of Quercus infectoria. Molecules. Vol.14, No.12 (2009), 4987-5000. doi:10.3390/molecules14124987 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/27321
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Hepatoprotective potential of extracts from seeds of Areca catechu and nutgalls of Quercus infectoria
Other Contributor(s)
Abstract
Aqueous extracts from seeds of Areca catechu L. (Arecaceae) (AC) and nutgalls of Quercus infectoria Oliv. (Fagaceae) (QI) were investigated for their hepatoprotective potential by studying their antioxidant capacity using four different methods, by determining their in vitro anti-inflammatory activity against 5-lipoxygenase, and by evaluating their hepatoprotective potential against liver injury induced by carbon tetrachloride (CCl4) in rats. AC and QI extracts exhibited potent antioxidant and anti-inflammatory activities. Treatment of rats with AC and QI extracts reversed oxidative damage in hepatic tissues induced by CCl4. It is suggested that extracts rich in either condensed or hydrolysable tannins and known for their potent antioxidant and anti-inflammatory activities, may potentially confer protection against oxidative stress-induced liver injury. These data should contribute to evidence-based traditional medicines for anti-inflammatory and hepatoprotective effects of both extracts.