Publication:
In vivo antiparasitic activity of the Thai traditional medicine plant-Tinospora crispa-against Plasmodium yoelii

1

Issued Date

2009-09-01

Resource Type

Article

ISSN

01251562

Other identifier(s)

2-s2.0-70349823679

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Southeast Asian Journal of Tropical Medicine and Public Health. Vol.40, No.5 (2009), 898-900

Suggested Citation

Thanaporn Rungruang, Thidarut Boonmars In vivo antiparasitic activity of the Thai traditional medicine plant-Tinospora crispa-against Plasmodium yoelii. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.40, No.5 (2009), 898-900. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/27948

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Title

In vivo antiparasitic activity of the Thai traditional medicine plant-Tinospora crispa-against Plasmodium yoelii

Author(s)

Thanaporn Rungruang
 Thidarut Boonmars

Other Contributor(s)

Mahidol University
 Khon Kaen University

Abstract

We investigated the in vivo antimalarial effect of crude extract of Tinospora crispa, a Thai traditional medicine plant. Mice were inoculated with Plasmodium yoelii then treated with the crude extract of Tinospora crispa at doses of 20, 40 and 80 mg/kg. Mice receiving the dose of 20 mg/kg died on average on Day 8. Mice remained alive longer when treated of the dose of 40 mg/kg or even longer under the treatment of the dose of 80 mg/kg. Surprisingly and interestingly, one mouse from the group in which the dose of 80 mg/kg was administrated is still alive and the parasite was cleared from the blood stream. In conclusion, T. crispa has an in vivo antimalarial effect in dose dependent manner.

Keyword(s)

Medicine

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https://repository.li.mahidol.ac.th/handle/123456789/27948

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