Publication: More realistic model for simulating min protein dynamics: Lattice Boltzmann method incorporating the role of nucleoids
3
Issued Date
2010-12-01
Resource Type
ISSN
20103778
2010376X
2010376X
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2-s2.0-84871181037
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Mahidol University
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SCOPUS
Bibliographic Citation
World Academy of Science, Engineering and Technology. Vol.43, (2010), 458-463
Suggested Citation
J. Yojina, W. Ngamsaad, N. Nuttavut, D. Triampo, Y. Lenbury, W. Triampo, P. Kanthang, S. Sriyab More realistic model for simulating min protein dynamics: Lattice Boltzmann method incorporating the role of nucleoids. World Academy of Science, Engineering and Technology. Vol.43, (2010), 458-463. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/29066
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Title
More realistic model for simulating min protein dynamics: Lattice Boltzmann method incorporating the role of nucleoids
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Abstract
The dynamics of Min proteins plays a center role in accurate cell division. Although the nucleoids may presumably play an important role in prokaryotic cell division, there is a lack of models to account for its participation. In this work, we apply the lattice Boltzmann method to investigate protein oscillation based on a mesoscopic model that takes into account the nucleoid's role. We found that our numerical results are in reasonably good agreement with the previous experimental results On comparing with the other computational models without the presence of nucleoids, the highlight of our finding is that the local densities of MinD and MinE on the cytoplasmic membrane increases, especially along the cell width, when the size of the obstacle increases, leading to a more distinct cap-like structure at the poles. This feature indicated the realistic pattern and reflected the combination of Min protein dynamics and nucleoid's role.