Publication: Therapeutic drug monitoring of lopinavir in human immunodeficiency virus-infected children receiving adult tablets
1
Issued Date
2010-01-01
Resource Type
ISSN
15320987
08913668
08913668
Other identifier(s)
2-s2.0-74049099818
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pediatric Infectious Disease Journal. Vol.29, No.1 (2010), 79-82
Suggested Citation
Thanyawee Puthanakit, Kulkanya Chokephaibulkit, Piyarat Suntarattiwong, Meena Gorowara, Nirun Vanprapar, Pimsiri Leawsrisuk, Tulathip Suwanlerk, Pitch Boonrak, Kiat Ruxrungtham Therapeutic drug monitoring of lopinavir in human immunodeficiency virus-infected children receiving adult tablets. Pediatric Infectious Disease Journal. Vol.29, No.1 (2010), 79-82. doi:10.1097/INF.0b013e3181b21040 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/29882
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Therapeutic drug monitoring of lopinavir in human immunodeficiency virus-infected children receiving adult tablets
Abstract
Because of the lack of a lopinavir/ritonavir (LPV/r) pediatric formulation, 54 HIV-infected children were given generic LPV/r adult tablets. Of 54 children, 21 took cut pills to get the appropriate dose. The median (interquartile range) LPV trough serum concentration (Ctrough) was 6.7 (5.0-9.9) mg/L. All the children had Ctrough >1.0 mg/L and 96% had values >4.0 mg/L. LPV/r adult tablets can be used in children when it is necessary. © 2009 by Lippincott Williams & Wilkins.