Crossed immunoelectrophoresis for the detection of split products of the third complement in dengue hemorrhagic fever. I. Observations in patients' plasma
American Journal of Tropical Medicine and Hygiene. Vol.32, No.3 (1983), 569-576
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V. Churdboonchart, N. Bhamarapravati, P. Futrakul Crossed immunoelectrophoresis for the detection of split products of the third complement in dengue hemorrhagic fever. I. Observations in patients' plasma. American Journal of Tropical Medicine and Hygiene. Vol.32, No.3 (1983), 569-576. doi:10.4269/ajtmh.1983.32.569 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/30480
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Crossed immunoelectrophoresis for the detection of split products of the third complement in dengue hemorrhagic fever. I. Observations in patients' plasma
Crossed immunoelectrophoresis was applied to detect the products of the third component of complement (C3) activation in plasma of patients suffering from dengue hemorrhagic fever (DHF), using inulin-treated normal human sera as positive control. In DHF, C3split products were demonstrated in severely ill patients classified as having Grade III and Grade IV disease. These split products rapidly disappeared during the convalescent phase. The appearance of C3activation products in DHF correlated well with signs of shock. This electropherogram of C3activation could be used as a parameter reflecting immunologic activity in dengue hemorrhagic fever.
