Publication: Convenient synthesis of α-nitrooximes mediated by OXONE®
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Issued Date
2014-01-01
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ISSN
20462069
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2-s2.0-84912038846
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Mahidol University
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SCOPUS
Bibliographic Citation
RSC Advances. Vol.4, No.104 (2014), 59726-59732
Suggested Citation
Napasawan Chumnanvej, Natthapol Samakkanad, Manat Pohmakotr, Vichai Reutrakul, Thaworn Jaipetch, Darunee Soorukram, Chutima Kuhakarn Convenient synthesis of α-nitrooximes mediated by OXONE®. RSC Advances. Vol.4, No.104 (2014), 59726-59732. doi:10.1039/c4ra11703d Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/33576
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Title
Convenient synthesis of α-nitrooximes mediated by OXONE®
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Abstract
© The Royal Society of Chemistry 2014. A novel OXONE® mediated direct difunctionalization of alkenes with NaNO<inf>2</inf> in aqueous acetonitrile for the synthesis of α-nitrooximes was developed. The α-nitrooximes were readily prepared in moderate to high yields at room temperature under mild reaction conditions. The present protocol offers an easy and environmentally benign approach to access various α-nitrooximes derived from styrene derivatives.