Publication: Liver adenomatosis: Serial investigation on MRI
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Issued Date
2014-01-01
Resource Type
ISSN
14320509
09428925
09428925
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2-s2.0-84897582212
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Mahidol University
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SCOPUS
Bibliographic Citation
Abdominal Imaging. Vol.39, No.2 (2014), 269-282
Suggested Citation
Saowanee Srirattanapong, Wirana Angthong, Bong Soo Kim, Paul Hideyo Hayashi, David A. Gerber, John T. Woosley, Jared Peacock, Anuruddika Ranatunga, Richard C. Semelka Liver adenomatosis: Serial investigation on MRI. Abdominal Imaging. Vol.39, No.2 (2014), 269-282. doi:10.1007/s00261-013-0056-y Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/33937
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Title
Liver adenomatosis: Serial investigation on MRI
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Abstract
Purpose: To describe the natural history of liver adenomatosis (LA), including complications and changes in lesion size over time. Materials and methods: Eighteen patients with clinical diagnosis of LA were included. Clinical and biochemical information were collected. The initial and follow-up MR studies were reviewed retrospectively to determine change in lesion size and imaging features. Results: Seventeen patients were women (94.4%). The mean age of the initial MR study was 37.0 years (18-52 years). The median size of the largest lesion was 6.7 cm (range 3.0-13.5 cm). Intratumoral bleeding was detected on MRI in 9 lesions, in 7 patients (38.8%). The median size for hemorrhagic lesions was 7.6 cm (range 4.1-13.5 cm). During the mean follow-up period of 29.4 (range 4-98) months, 10 patients had stable disease (55.6%), and 8 patients had tumor regression (44.4% ). Of 8 patients who were followed without intervention, 3 patients (37.5%) had spontaneous regression. No malignant transformation or lesion progression was occurred. Conclusion: During an over 2-year follow-up period, the majority of lesions of LA appeared to remain stable or showed tumor regression. Spontaneous tumor regression can be observed in approximately 37% of individuals in the age range of 28-53 years. © Springer Science+Business Media 2013.