Publication: High Urinary Iodine Concentration Among Breastfed Infants and the Factors Associated with Iodine Content in Breast Milk
1
Issued Date
2018-11-01
Resource Type
ISSN
15590720
01634984
01634984
Other identifier(s)
2-s2.0-85044085162
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Biological Trace Element Research. Vol.186, No.1 (2018), 106-113
Suggested Citation
Oraporn Dumrongwongsiri, Suthida Chatvutinun, Phanphen Phoonlabdacha, Areeporn Sangcakul, La or Chailurkit, Atitaya Siripinyanond, Umaporn Suthutvoravut, Nalinee Chongviriyaphan High Urinary Iodine Concentration Among Breastfed Infants and the Factors Associated with Iodine Content in Breast Milk. Biological Trace Element Research. Vol.186, No.1 (2018), 106-113. doi:10.1007/s12011-018-1303-4 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/45004
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
High Urinary Iodine Concentration Among Breastfed Infants and the Factors Associated with Iodine Content in Breast Milk
Other Contributor(s)
Abstract
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Iodine deficiency in infants leads to delayed growth and development. Some studies have reported iodine deficiency among infants and lactating women. We assessed iodine status in infants and lactating women, as well as the iodine content in breast milk. A cross-sectional study enrolled mother-infant pairs (infants aged 4–6 months), who visited Well Child Clinic at Ramathibodi Hospital, Bangkok, Thailand. Infants were classified by feeding type as breastfed (BF), mixed breastfed and formula-fed (MF), and formula-fed (FF). Demographic and perinatal data were collected. The urinary iodine concentration (UIC) of infants and lactating women, and breast milk iodine concentration (BMIC) were analyzed. Seventy-one infants were enrolled. The median UIC of infants was 282 mcg/L. Breastfed infants had higher median UIC than formula-fed infants (553 vs. 192 mcg/L; p = 0.002). Forty-eight percent of infants had a UIC more than 300 mcg/L. The median UIC and BMIC of lactating women were 149 and 255 mcg/L, respectively. Among the BF group, the infant UIC was correlated with maternal UIC (r s = 0.857, p = 0.014). Multiple linear regression showed the BMIC to be associated with maternal UIC (β = 4.03, 95% CI [1.34, 6.71]) and maternal weight (β = 8.26, 95%CI [2.76, 13.77]). Iodine nutrition among our study population was adequate. The median UIC of infants and lactating mothers were 282 and 149 mcg/L, respectively. Breastfed infants had a significantly higher median UIC than formula-fed infants. The BMIC was associated with maternal UIC and maternal weight.