Publication: Stereoselective Synthesis of Tetrahydrofuran Lignans
Issued Date
2018-12-17
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ISSN
1437210X
00397881
00397881
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2-s2.0-85058034792
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Mahidol University
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SCOPUS
Bibliographic Citation
Synthesis (Germany). Vol.50, No.24 (2018), 4746-4764
Suggested Citation
Darunee Soorukram, Manat Pohmakotr, Chutima Kuhakarn, Vichai Reutrakul Stereoselective Synthesis of Tetrahydrofuran Lignans. Synthesis (Germany). Vol.50, No.24 (2018), 4746-4764. doi:10.1055/s-0037-1610289 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/45406
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Title
Stereoselective Synthesis of Tetrahydrofuran Lignans
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Abstract
© Georg Thieme Verlag Stuttgart · New York. This short review aims to summarize the reports on stereoselective synthesis of naturally occurring tetrahydrofuran lignans published during the period of 2006 to 2018. The stereoselective construction of non-natural tetrahydrofuran frameworks is not included in this review. 1 Introduction 2 Stereoselective Synthesis of 2,5-Diaryltetrahydrofuran (CL5-a) 2.1 Synthesis of CL5-a via Friedel-Crafts Arylation or Nucleophilic Addition/Reduction of γ-Butyrolactones 2.2 Synthesis of CL5-a via Intramolecular Cyclization of 1,4-Diarylbutanediols 2.3 Synthesis of CL5-a via Diastereoselective Hydrogenation of Furan Derivatives 2.4 Synthesis of CL5-a via Cycloaddition Reaction of Substituted Cyclopropane Derivatives 3 Stereoselective Synthesis of 2-Aryl-4-benzyltetrahydrofuran (CL5-b) 4 Stereoselective Synthesis of 3,4-Dibenzyltetrahydrofuran (CL5-c) 5 Conclusions.