Publication: Four-dimensional computed tomography pattern enhancement of parathyroid lesions in preoperative localization of hyperparathyroidism
Submitted Date
Received Date
Accepted Date
Issued Date
2019-05-01
Copyright Date
Announcement No.
Application No.
Patent No.
Valid Date
Resource Type
Edition
Resource Version
Language
File Type
No. of Pages/File Size
ISBN
ISSN
01252208
eISSN
DOI
Scopus ID
WOS ID
Pubmed ID
arXiv ID
Call No.
Other identifier(s)
2-s2.0-85068785565
Journal Title
Volume
Issue
item.page.oaire.edition
Start Page
End Page
Access Rights
Access Status
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Physical Location
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.102, No.5 (2019), 576-581
Citation
D. Songsaeng, T. Sricharoen, B. Khiewvan, P. Pusuwan, S. Chuthapisith, S. Sriussadaporn, T. Kunavisarut, W. Pongsapich, N. Chamsri, C. Boonma, A. Suwanbundit (2019). Four-dimensional computed tomography pattern enhancement of parathyroid lesions in preoperative localization of hyperparathyroidism. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/51679.
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Four-dimensional computed tomography pattern enhancement of parathyroid lesions in preoperative localization of hyperparathyroidism
Alternative Title(s)
Author's Affiliation
Author's E-mail
Editor(s)
Editor's Affiliation
Corresponding Author(s)
Creator(s)
Compiler
Advisor(s)
Illustrator(s)
Applicant(s)
Inventor(s)
Issuer
Assignee
Other Contributor(s)
Series
Has Part
Abstract
© JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND | 2019. Background: Four-dimensional computed tomography (4D-CT) improves the precision of pre-operative localization of hyperfunctioning parathyroid glands (HPGs). Objective: To analyze the role of pattern enhancement in 4D-CT imaging in hyperparathyroidism for differentiating HPGs from surrounding tissues for precision pre-operative localization of HPGs. Materials and Methods: The present retrospective study was conducted in patients who underwent 4D-CT scan of the parathyroid at the Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand between January 2013 and October 2016. Lesions were plotted for pattern enhancement, and mean Hounsfield units (HUs) of HPGs, lymph nodes, thyroid nodules, and thyroid glands were measured and analyzed. Results: Twenty-seven patients with 119 lesions were included. Significant difference was observed between both parathyroid adenoma and hyperplasia and thyroid gland during non-contrast phase and delayed 90-second phase. Attenuation value of less than 60 HUs in pre-contrast phase could differentiate HPGs from thyroid gland with 60% sensitivity and 85% specificity. Sensitivity of 4D-CT was 100% (95% Cl 73.5 to 100) for localization of all HPGs. Conclusion: Integration of clinical history data, conventional imaging, and 4D-CT imaging could improve differentiation of HPGs from surrounding tissues, thereby improving the precision of HPG localization during minimally invasive parathyroidectomy.