Publication: Predictive Value of Susceptibility Vessel Sign for Arterial Recanalization and Clinical Improvement in Ischemic Stroke
Issued Date
2019-02-01
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ISSN
15244628
Other identifier(s)
2-s2.0-85060617338
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Mahidol University
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SCOPUS
Bibliographic Citation
Stroke. Vol.50, No.2 (2019), 512-515
Suggested Citation
Jean Darcourt, Pattarawit Withayasuk, Ivan Vukasinovic, Caterina Michelozzi, Guillaume Bellanger, Adrien Guenego, Gilles Adam, Margaux Roques, Anne Christine Januel, Philippe Tall, Olivier Meyrignac, Vanessa Rousseau, Cédric Garcia, Jean François Albucher, Bernard Payrastre, Fabrice Bonneville, Jean Marc Olivot, Christophe Cognard Predictive Value of Susceptibility Vessel Sign for Arterial Recanalization and Clinical Improvement in Ischemic Stroke. Stroke. Vol.50, No.2 (2019), 512-515. doi:10.1161/STROKEAHA.118.022912 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/51921
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Title
Predictive Value of Susceptibility Vessel Sign for Arterial Recanalization and Clinical Improvement in Ischemic Stroke
Author(s)
Jean Darcourt
Pattarawit Withayasuk
Ivan Vukasinovic
Caterina Michelozzi
Guillaume Bellanger
Adrien Guenego
Gilles Adam
Margaux Roques
Anne Christine Januel
Philippe Tall
Olivier Meyrignac
Vanessa Rousseau
Cédric Garcia
Jean François Albucher
Bernard Payrastre
Fabrice Bonneville
Jean Marc Olivot
Christophe Cognard
Pattarawit Withayasuk
Ivan Vukasinovic
Caterina Michelozzi
Guillaume Bellanger
Adrien Guenego
Gilles Adam
Margaux Roques
Anne Christine Januel
Philippe Tall
Olivier Meyrignac
Vanessa Rousseau
Cédric Garcia
Jean François Albucher
Bernard Payrastre
Fabrice Bonneville
Jean Marc Olivot
Christophe Cognard
Abstract
Background and Purpose- Our goal was to evaluate whether the presence of a low signal intensity known as susceptibility vessel sign (SVS) on T2*-gradient echo imaging sequence was predictive of arterial recanalization and the early clinical improvement after mechanical thrombectomy. Methods- This observational study was based on a prospective database of acute ischemic strokes treated by mechanical thrombectomy. Inclusion criteria were patients with acute anterior ischemic stroke, diagnosed by magnetic resonance imaging, including a T2*-gradient echo imaging sequence, and treated by mechanical thrombectomy. Two independent readers assessed the presence of an SVS. Successful recanalization was defined as a Thrombolysis in Cerebral Infarction score of 2b-3 after mechanical thrombectomy. Early clinical improvement was estimated by the difference between the baseline National Institutes of Health Stroke Scale and the National Institutes of Health Stroke Scale on day 1 after treatment Results- The SVS was detected in 137 (76%) out of 180 patients. The kappa interrater agreement was 0.71 with a 95% CI of 0.59 to 0.82. Successful recanalization was associated with an SVS+ with odds ratio, 2.48; 95% CI, 1.05-5.74; P=0.03. The early clinical improvement was better in patients with an SVS+ (median, -6; interquartile range, -11 to 0) compared with SVS- patients (median, -1; interquartile range, -10 to 3) with P=0.01. Conclusions- The visualization of SVS is a reliable and easily accessible predictive factor of recanalization success and early clinical improvement.