Publication: Presence of residual venous thrombus at warfarin withdrawal: A predictor for recurrence after a first episode of symptomatic provoked proximal deep venous thrombosis in thai population?
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Issued Date
2019-01-01
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22288082
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2-s2.0-85077621624
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Mahidol University
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SCOPUS
Bibliographic Citation
Siriraj Medical Journal. Vol.71, No.6 (2019), 486-490
Suggested Citation
Kanin Pruekprasert, Chanean Ruangsetakit, Chumpol Wongwanit, Khamin Chinsakchai, Kiattisak Hongku, Nattawut Puangpanngam, Jutapim Khayankit, Tze Tec Chong, Nuttawut Sermsathanasawadi Presence of residual venous thrombus at warfarin withdrawal: A predictor for recurrence after a first episode of symptomatic provoked proximal deep venous thrombosis in thai population?. Siriraj Medical Journal. Vol.71, No.6 (2019), 486-490. doi:10.33192/Smj.2019.72 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/52199
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Title
Presence of residual venous thrombus at warfarin withdrawal: A predictor for recurrence after a first episode of symptomatic provoked proximal deep venous thrombosis in thai population?
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Abstract
© 2019, Faculty of Medicine Siriraj Hospital, Mahidol University. Objective: To assess the risk for venous thromboembolism (VTE) recurrence by presence of residual venous thrombus (RVT) at warfarin withdrawal following symptomatic first provoked proximal DVT. Methods: Medical records of 45 consecutive patients with symptomatic first provoked proximal DVTs who had undergone warfarin surveillance for ≥ 3 months were reviewed retrospectively. Altogether, 22 patients discontinued anticoagulation after ≥ 3 months regardless of duplex ultrasonography results of RVT diagnosed by compression ultrasonography. Another 23 patients discontinued anticoagulation after the RVT disappeared. Primary outcome was recurrent VTE. Results: Four of the 45 patients experienced recurrent VTE (8.89%), including 2 (9.00%) of 22 patients who had discontinued anticoagulant regardless of duplex ultrasonography results and 2 (8.70%) of 23 patients who discontinued anticoagulation after RVT disappearance (p = 0.963). All of the recurrent VTE were recurrent DVT. Conclusion: RVT at warfarin withdrawal was not a predictor for recurrence VTE following a first symptomatic provoked proximal DVT.