Publication:
High blood pressure in dementia: How low can we go?

2

Issued Date

2020-03-01

Resource Type

Review

ISSN

17517176
15246175

DOI

10.1111/jch.13752

Other identifier(s)

2-s2.0-85076377016

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Journal of Clinical Hypertension. Vol.22, No.3 (2020), 415-422

Suggested Citation

Yuda Turana, Jeslyn Tengkawan, Yook Chin Chia, Boon Wee Teo, Jinho Shin, Guru Prasad Sogunuru, Arieska Ann Soenarta, Huynh Van Minh, Peera Buranakitjaroen, Chen Huan Chen, Jennifer Nailes, Satoshi Hoshide, Sungha Park, Saulat Siddique, Jorge Sison, Apichard Sukonthasarn, Jam Chin Tay, Tzung Dau Wang, Narsingh Verma, Yu Qing Zhang, Ji Guang Wang, Kazuomi Kario High blood pressure in dementia: How low can we go?. Journal of Clinical Hypertension. Vol.22, No.3 (2020), 415-422. doi:10.1111/jch.13752 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/54624

Research Projects

Organizational Units

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Journal Issue

Thesis

Title

High blood pressure in dementia: How low can we go?

Author(s)

Yuda Turana
 Jeslyn Tengkawan
 Yook Chin Chia
 Boon Wee Teo
 Jinho Shin
 Guru Prasad Sogunuru
 Arieska Ann Soenarta
 Huynh Van Minh
 Peera Buranakitjaroen
 Chen Huan Chen
 Jennifer Nailes
 Satoshi Hoshide
 Sungha Park
 Saulat Siddique
 Jorge Sison
 Apichard Sukonthasarn
 Jam Chin Tay
 Tzung Dau Wang
 Narsingh Verma
 Yu Qing Zhang
 Ji Guang Wang
 Kazuomi Kario

Other Contributor(s)

De La Salle Health Sciences Institute
 Sunway University
 National University Health System
 Hanyang University Medical Center
 Jichi Medical University
 Yonsei University Health System
 Shanghai Jiao Tong University School of Medicine
 Madras Institute of Orthopaedics and Traumatology Hospitals
 Kathmandu University
 University of the East Ramon Magsaysay Memorial Medical Center
 Hue University
 Fatima Memorial Hospital
 Universitas Katolik Indonesia Atma Jaya
 Universitas Indonesia
 University of Malaya
 Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
 Yong Loo Lin School of Medicine
 National Taiwan University College of Medicine
 King George's Medical University
 Faculty of Medicine, Siriraj Hospital, Mahidol University
 National Yang-Ming University, School of Medicine
 Tan Tock Seng Hospital
 Chiang Mai University

Abstract

© 2019 Wiley Periodicals, Inc. Hypertension is an important public health concern. The prevalence keeps increasing, and it is a risk factor for several adverse health outcomes including a decline in cognitive function. Recent data also show that the prevalence of hypertension and age-related dementia is rising in Asian countries, including in the oldest old group. This study aims to discuss possible treatments for high blood pressure in the elderly and propose an optimal target for BP relative to cognitive outcomes. This review discusses several studies on related blood pressure treatments that remain controversial and the consequences if the treatment target is too low or aggressive. Longitudinal, cross-sectional, and RCT studies were included in this review. An optimum systolic blood pressure of 120-130 mm Hg is recommended, especially in nondiabetic hypertensive patients with significant risk factors. In the oldest old group of patients, hypertension might have a protective effect. The use of calcium channel blockers (CCB) and angiotensin receptor blocker (ARB) is independently associated with a decreased risk of dementia in older people. However, personalized care for patients with hypertension, especially for patients who are frail or very old, is encouraged.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/54624

Collections

Scopus 2020