Publication: Disseminated histoplasmosis in a kidney transplant patient
6
Issued Date
2020-01-01
Resource Type
ISSN
13993062
13982273
13982273
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2-s2.0-85088383195
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Mahidol University
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SCOPUS
Bibliographic Citation
Transplant Infectious Disease. (2020)
Suggested Citation
Taksaon Angsutararux, Piriyaporn Chongtrakool, Sanya Sukpanichnant, Kornpawee Wongwaipijarn, Walaiporn Wangchinda Disseminated histoplasmosis in a kidney transplant patient. Transplant Infectious Disease. (2020). doi:10.1111/tid.13405 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/58239
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Title
Disseminated histoplasmosis in a kidney transplant patient
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Abstract
© 2020 Wiley Periodicals LLC Patients with impaired cell-mediated immunity have a higher risk of developing histoplasmosis; however, histoplasmosis after solid organ transplantation is rare. In Thailand, histoplasmosis cases are sporadic, and most cases are associated with human immunodeficiency virus (HIV) infection. Herein, we report a case of disseminated histoplasmosis in a kidney transplant Thai recipient diagnosed by fungal staining of fungal culture from bronchoalveolar lavage and bone marrow biopsy. Liposomal amphotericin B was given followed by oral itraconazole. The patient's clinical condition was improved; however, his graft function was irreversibly declined. The majority of histoplasmosis cases after solid organ transplant presented with disseminated disease with pulmonary involvement. Even in a non-endemic area of histoplasmosis, suspected cases should be early diagnosed and promptly managed in order to reduce morbidity and mortality, especially in cell-mediated immunity defect patients like solid organ transplant recipients.
