Publication: Prevalence and subtype distribution of blastocystis infection in patients with diabetes mellitus in Thailand
Issued Date
2020-12-01
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ISSN
16604601
16617827
16617827
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2-s2.0-85097037827
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Environmental Research and Public Health. Vol.17, No.23 (2020), 1-12
Suggested Citation
Noppon Popruk, Satakamol Prasongwattana, Aongart Mahittikorn, Attakorn Palasuwan, Supaluk Popruk, Duangdao Palasuwan Prevalence and subtype distribution of blastocystis infection in patients with diabetes mellitus in Thailand. International Journal of Environmental Research and Public Health. Vol.17, No.23 (2020), 1-12. doi:10.3390/ijerph17238877 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/60475
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Title
Prevalence and subtype distribution of blastocystis infection in patients with diabetes mellitus in Thailand
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Abstract
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Diabetes mellitus (DM) is a major global public health problem with an increasing prevalence. DM increases the risk of infections caused by bacteria, fungi, viruses, and parasites. We examined the prevalence, subtypes, and risk factors of Blastocystis infection in patients with and without DM in central Thailand. Stool samples and questionnaires were obtained from 130 people in the DM group and 100 people in the non-DM group. Blastocystis infection was identified via a nested polymerase chain reaction and subtyped via sequencing of the partial small-subunit ribosomal RNA (SSU rRNA) gene. Analysis of potential risk factors was conducted via binary logistic regression. The overall prevalence of Blastocystis infection was 10.8%, including rates of 9% and 12.3% in the non-DM and DM groups, respectively. The most prevalent subtype was ST3, followed by ST1, and ST4. Factors that potentially increased the risk of Blastocystis infection include patients being >65 years old, the presence of DM, a DM duration of ≥10 years, a low level of education, and animal ownership. In conclusion, this is the first study of Blastocystis infection in DM, and a high prevalence was found among this population. Therefore, health education promoting sanitation and hygiene is necessary to reduce and prevent infection in the community.