Publication: Magnetic resonance imaging assessment of aortic dilatation and distensibility in 269 patients with repaired tetralogy of Fallot
Issued Date
2021-08-01
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ISSN
1867108X
18671071
18671071
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2-s2.0-85104450084
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Mahidol University
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SCOPUS
Bibliographic Citation
Japanese Journal of Radiology. Vol.39, No.8 (2021), 774-782
Suggested Citation
Suvipaporn Siripornpitak, Apichaya Sriprachyakul, Saruntorn Wongmetta, Piya Samankatiwat, Pirapat Mokarapong, Suthep Wanitkun Magnetic resonance imaging assessment of aortic dilatation and distensibility in 269 patients with repaired tetralogy of Fallot. Japanese Journal of Radiology. Vol.39, No.8 (2021), 774-782. doi:10.1007/s11604-021-01119-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/78016
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Title
Magnetic resonance imaging assessment of aortic dilatation and distensibility in 269 patients with repaired tetralogy of Fallot
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Abstract
Purpose: To determine the prevalence and degree of aortic dilatation (Adilatation), severity of aortic stiffness (Astiff), factors for Adilatation, and level of aortic root most sensitive to Astiff in patients with repaired tetralogy of Fallot (rTOF). Materials and methods: 269 patients with rTOF (mean age 14.9 ± standard deviation 5.0 years) were analyzed for Adilatation at annulus, sinus, sinotubular junction, and ascending aorta (aAo). Aortic size index was graded as Z score < 2, 2–2.99, 3–4.99 and ≥ 5. Aortic distensibility (aAdis) was categorized according to 4 aortic levels and dilatation severity. Factors for Adilatation and level of aortic root most sensitive to Astiff were analyzed. Results: Sinus and aAo were the two most common sites of Adilatation, with a prevalence of 84% and 76%, respectively. A decreased aAdis was found (mean 5.38 ± 1.79 10−3 mmHg−1). aAdis only declined significantly at the sinus level (p = 0.009). Male sex, age-at-repair and aortic regurgitation were significant factors for Adilatation, with male sex as the strongest factor (odds ratio 2.94). There was a significant decline in aAdis at sinus level (p = 0.002) as Adilatation progressed. Conclusions: We observed a high prevalence of Adilatation and Astiff in patients with rTOF. Male sex is the strongest factor for Adilatation. The sinus is the most sensitive area for determining a negative aAdis effect.