Publication: The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools
Issued Date
2021-04-01
Resource Type
ISSN
15491676
15491277
15491277
Other identifier(s)
2-s2.0-85104922186
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
PLoS Medicine. Vol.18, No.4 (2021)
Suggested Citation
Sarah Auburn, Qin Cheng, Jutta Marfurt, Ric N. Price The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools. PLoS Medicine. Vol.18, No.4 (2021). doi:10.1371/journal.pmed.1003560 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/78286
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Title
The changing epidemiology of Plasmodium vivax: Insights from conventional and novel surveillance tools
Author(s)
Abstract
Renewed efforts to eliminate malaria have had greater impact on Plasmodium falciparum AU : Pleasenotethatasp than Plasmodium vivax, a reflection of the fundamental differences in the biology of the parasite, its transmission dynamics, and ability to form dormant liver stages. • The main burden of P. vivax malaria is in young children residing in remote communities with poor access to healthcare services. • The decline in P. vivax malaria has led to an increasing proportion of the parasite reservoir occurring in asymptomatic and low-density P. vivax infections and heterogeneous patterns of parasite transmission. • Genetic tools to study the spatial and temporal patterns of P. vivax transmission in different endemicities and ultrasensitive PCR (uPCR)-based techniques are expanding our knowledge of the magnitude and biology of low-density P. vivax infections. • Serology offers alternative ways of detecting recent P. vivax infections and monitoring of the impact of public health interventions at very low endemicity.