Antimicrobial thermoplastic starch reactive blend with chlorhexidine gluconate and epoxy resin
2
Issued Date
2023-02-01
Resource Type
ISSN
01448617
Scopus ID
2-s2.0-85142245533
Pubmed ID
36446505
Journal Title
Carbohydrate Polymers
Volume
301
Rights Holder(s)
SCOPUS
Bibliographic Citation
Carbohydrate Polymers Vol.301 (2023)
Suggested Citation
Thajai N., Rachtanapun P., Thanakkasaranee S., Chaiyaso T., Phimolsiripol Y., Leksawasdi N., Sommano S.R., Sringarm K., Chaiwarit T., Ruksiriwanich W., Jantrawut P., Kodsangma A., Ross S., Worajittiphon P., Punyodom W., Jantanasakulwong K. Antimicrobial thermoplastic starch reactive blend with chlorhexidine gluconate and epoxy resin. Carbohydrate Polymers Vol.301 (2023). doi:10.1016/j.carbpol.2022.120328 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/81991
Title
Antimicrobial thermoplastic starch reactive blend with chlorhexidine gluconate and epoxy resin
Author's Affiliation
Other Contributor(s)
Abstract
An antimicrobial thermoplastic starch (TPS) was developed by melt-mixing TPS with chlorhexidine gluconate (CHG) and epoxy resin (Er). The tensile strength and hardness of the TPSCh blend increased with the addition of Er (TPSCh/Er), especially at 5 wt% Er (TPSCh/Er5) (19.5 MPa and 95 %, respectively). The water contact angle of TPSCh/Er was higher than those of TPS and TPSCh because of the improved interfacial tension. Fourier transform infrared and nuclear magnetic resonance analyses confirmed the reaction between the epoxy groups of Er, hydroxyl groups of starch, and amino groups of CHG. TPSCh/Er5 exhibited a significantly lower CHG release than TPSCh owing to the rearrangement of TPSCh chains via Er crosslinking. TPSCh/Er0.5 and TPSCh/Er1 showed inhibition zones against both tested bacteria (Staphylococcus aureus and Bacillus cereus), whereas TPSCh/Er2.5, TPSCh/Er5, and TPSCh/Er10 showed inhibition zones only against S. aureus. Moreover, TPSCh and TPSCh/Er0.5–2.5 exhibited inhibition zones with Saccharomyces cerevisiae.