Publication: Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria
3
Accepted Date
2013-01-18
Issued Date
2013
Copyright Date
2013
Resource Type
Language
eng
ISSN
2090-2158 (electronic)
2090-214X (printed)
2090-214X (printed)
Rights
Mahidol University
Rights Holder(s)
Hindawi
Bibliographic Citation
Thanachartwet V, Desakorn V, Sahassananda D, Kyaw Win KK, Supaporn T. Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria. Int J Nephrol. 2013;2013:841518.
Suggested Citation
Vipa Thanachartwet, วิภา ธนาชาติเวทย์, Varunee Desakorn, วารุณี เทศะกรณ์, Duangjai Sahassananda, ดวงใจ สหัสสานนท์, Kyaw Win, Ko Ko Yazar, Thanom Supaporn Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria. Thanachartwet V, Desakorn V, Sahassananda D, Kyaw Win KK, Supaporn T. Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria. Int J Nephrol. 2013;2013:841518.. doi:10.1155/2013/841518 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/841
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Title
Acute Renal Failure in Patients with Severe Falciparum Malaria: Using the WHO 2006 and RIFLE Criteria
Corresponding Author(s)
Abstract
There are limited data on the application of the RIFLE criteria among patients
with severe malaria. This retrospective study was conducted by reviewing 257
medical records of adult hospitalized patients with severe falciparum malaria at
the Mae Sot General Hospital, Tak province in the northern part of Thailand. The
aims of this study were to determine the incidence of acute renal failure (ARF)
in patients with severe falciparum malaria and its association with RRT as well
as in-hospital mortality. Using the WHO 2006 criteria, ARF was the second most
common complication with incidence of 44.7% (115 patients). The requirement for
RRT was 45.2% (52 patients) and the in-hospital mortality was 31.9% (36
patients). Using the RIFLE criteria, 73.9% (190 patients) had acute kidney injury
(AKI). The requirement for RRT was 11.6% (5 patients) in patients with RIFLE-I
and 44.9% (48 patients) in patients with RIFLE-F. The in-hospital mortality
gradually increased with the severity of AKI. The requirement for RRT (P < 0.05)
and the in-hospital mortality (P < 0.05) were significantly higher in ARF
patients with severe falciparum malaria using both criteria. In conclusion, the
RIFLE criteria could be used for diagnosing AKI and predicting outcomes in
patients with severe malaria similar to the WHO 2006 criteria.