Phytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice)
16
Issued Date
2022-10-01
Resource Type
ISSN
22314040
eISSN
09762094
Scopus ID
2-s2.0-85140716015
Journal Title
Journal of Advanced Pharmaceutical Technology and Research
Volume
13
Issue
4
Start Page
312
End Page
316
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Advanced Pharmaceutical Technology and Research Vol.13 No.4 (2022) , 312-316
Suggested Citation
Rungruang R., Peasura N., Kaisangsri N. Phytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice). Journal of Advanced Pharmaceutical Technology and Research Vol.13 No.4 (2022) , 312-316. 316. doi:10.4103/japtr.japtr_458_22 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/86829
Title
Phytochemical screening, quantitative analysis of cyanidin-3-O-glucoside content, and anticancer activity of novel rice bran (Tubtim Chumphae rice)
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
The objective of this research was to explore the phytochemicals in Tubtim Chumphae rice bran and determine their potential antioxidant and anticancer activities. The rice bran extract contained total phenolics, flavonoids, and anthocyanins as the major compounds. In addition, it exhibited the highest DPPH•, followed by ABTS•+, and FRAP radical scavenging activity. Moreover, the cytotoxic effect of the extract on Hep G2, SW620, KATO-III, BT474, and ChaGo-K-1 cancer cell lines was investigated; the obtained IC50 values were 144.6 ± 0.39, 116.9 ± 0.68, 99.6 ± 0.10, 94.4 ± 0.33, and 25.6 ± 0.45 μg/mL, respectively. Overall, the abovementioned results suggest that rice bran extract has potent anticancer activity owing to the induction of cell death in cancer cell lines.