Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
Issued Date
2022-05-01
Resource Type
eISSN
20513380
DOI
Scopus ID
2-s2.0-85128864062
Journal Title
Respirology Case Reports
Volume
10
Issue
5
Rights Holder(s)
SCOPUS
Bibliographic Citation
Respirology Case Reports Vol.10 No.5 (2022)
Suggested Citation
Palamit A., Tovichien P., Amornsitthiwat R. Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children. Respirology Case Reports Vol.10 No.5 (2022). doi:10.1002/rcr2.945 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/87319
Title
Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
Author(s)
Author's Affiliation
Other Contributor(s)
Abstract
Even though tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is usually found in HIV-positive patients receiving antiviral treatment, it can also occur in HIV-negative patients especially if they have risk factors. We report a unique case of TB-IRIS in an immunocompetent child presenting with new onset of pleuritic chest pain after receiving anti-TB drugs. TB-IRIS should be considered as a differential diagnosis in case of clinical deterioration or appearance of new typical lesions despite appropriate anti-TB treatment for more than 2 weeks in the absence of persistently active TB or any other alternative causes. This will prevent physicians from misdiagnosis as superimposed infections, treatment failure or TB relapse.