Potential Therapeutic Approaches for Chronic Urticaria: Beyond H1-Antihistamines and Biologics
Issued Date
2023-08-01
Resource Type
ISSN
22132198
Scopus ID
2-s2.0-85166923711
Pubmed ID
37356753
Journal Title
Journal of Allergy and Clinical Immunology: In Practice
Volume
11
Issue
8
Start Page
2265
End Page
2273
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of Allergy and Clinical Immunology: In Practice Vol.11 No.8 (2023) , 2265-2273
Suggested Citation
Zuberbier T., Peter J., Staubach P., Chularojanamontri L., Kulthanan K. Potential Therapeutic Approaches for Chronic Urticaria: Beyond H1-Antihistamines and Biologics. Journal of Allergy and Clinical Immunology: In Practice Vol.11 No.8 (2023) , 2265-2273. 2273. doi:10.1016/j.jaip.2023.06.027 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/88355
Title
Potential Therapeutic Approaches for Chronic Urticaria: Beyond H1-Antihistamines and Biologics
Other Contributor(s)
Abstract
Chronic urticaria is a disease that can significantly impact a patient's quality of life and ability to function. There are effective treatment options, such as nonsedating antihistamines or biologics, but some patients do not respond to these therapies, or the therapies are not available or affordable to all patients. This review aims to summarize potential treatment strategies for patients (1) who do not respond to antihistamines and (2) cannot readily access or do not respond to biologics. The review emphasizes the importance of sound clinical practice, including correct diagnosis of chronic urticaria phenotypes, treatment of associated comorbidities, and consideration of add-on pharmacological and nonpharmacological approaches. Although some treatments may lack high-quality evidence, they may still be justifiable in certain cases, provided that there is shared decision-making, regular reassessment, and early recognition of adverse events.