Image-guided core-needle or surgical biopsy for neuroblastoma diagnosis in children: A systematic review and meta-analysis from the International Society of Pediatric Surgical Oncology (IPSO)
1
Issued Date
2023-01-01
Resource Type
ISSN
15455009
eISSN
15455017
Scopus ID
2-s2.0-85177817844
Journal Title
Pediatric Blood and Cancer
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pediatric Blood and Cancer (2023)
Suggested Citation
Pio L., Brisse H.J., Alaggio R., Zambaiti E., Stenman J., Giuliani S., Montano V., Hinojosa A.S., Hoel A.T., Pevere A., Abu-Zaid A., Franchi-Abella S., Abdelhafeez A.H., Davidoff A.M., Losty P.D. Image-guided core-needle or surgical biopsy for neuroblastoma diagnosis in children: A systematic review and meta-analysis from the International Society of Pediatric Surgical Oncology (IPSO). Pediatric Blood and Cancer (2023). doi:10.1002/pbc.30789 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/91313
Title
Image-guided core-needle or surgical biopsy for neuroblastoma diagnosis in children: A systematic review and meta-analysis from the International Society of Pediatric Surgical Oncology (IPSO)
Author's Affiliation
Ramathibodi Hospital
Oslo Universitetssykehus
Ospedale F. del Ponte
Institut Curie
University of Liverpool
St. Jude Children's Research Hospital
Great Ormond Street Hospital for Children NHS Foundation Trust
IRCCS Ospedale Pediatrico Bambino Gesù
Hôpital Armand-Trousseau
Hopital de Bicetre
Hospital Regional Universitario Carlos Haya
UCL Great Ormond Street Institute of Child Health
Karolinska Institutet
Ospedale Infantile Regina Margherita
University of Tennessee Health Science Center
Oslo Universitetssykehus
Ospedale F. del Ponte
Institut Curie
University of Liverpool
St. Jude Children's Research Hospital
Great Ormond Street Hospital for Children NHS Foundation Trust
IRCCS Ospedale Pediatrico Bambino Gesù
Hôpital Armand-Trousseau
Hopital de Bicetre
Hospital Regional Universitario Carlos Haya
UCL Great Ormond Street Institute of Child Health
Karolinska Institutet
Ospedale Infantile Regina Margherita
University of Tennessee Health Science Center
Other Contributor(s)
Abstract
Background: Image-guided core-needle biopsy (IGCNB) is a widely used and valuable clinical tool for tissue diagnosis of pediatric neuroblastoma. However, open surgical biopsy remains common practice even if children undergo more invasive and painful procedures. This review aims to determine the diagnostic accuracy and safety of IGCNBs in pediatric patients with neuroblastoma. Methods: We conducted a systematic review of peer-reviewed original articles published between 1980 and 2023, by searching “pediatric oncology,” “biopsy,” “interventional radiology,” and “neuroblastoma.” Exclusion criteria were patients older than 18 years, studies concerning non-neurogenic tumors, case reports, and language other than English. Both the systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Results: A total of 533 abstracts articles were analyzed. Of these, eight retrospective studies met inclusion criteria (490 infants, 270 surgical biopsies [SB], 220 image-guided biopsies). Tissue adequacy for primary diagnosis (SB: n = 265, 98%; IGCNB: n = 199, 90%; p =.1) and biological characterization (SB: n = 186, 95%; IGCNB: n = 109, 89%; p =.15) was similar with both biopsy techniques, while intraoperative transfusion rate (SB: n = 51, 22%; IGCNB: n = 12, 6%; p =.0002) and complications (%) (SB: n = 58, 21%; IGCNB: n = 14, 6%; p =.005) were higher with surgical biopsy. Length of stay was similar in both groups; however, no additional data about concurrent diagnostic or treatment procedures were available in the analyzed studies. Conclusions: IGCNB is a safe and effective strategic approach for diagnostic workup of NB and should be considered in preferance to SB wherever possible.