Publication: Revision of the NMR assignments of pterostlbene and of dihydrodehydrodiconiferyl alcohol: Cytotoxic constituents from anogeissus acuminata
1
Issued Date
1994-07-01
Resource Type
ISSN
10575634
Other identifier(s)
2-s2.0-0027965141
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Natural Product Letters. Vol.4, No.4 (1994), 267-272
Suggested Citation
Agnes M. Rimando, John M. Pezzuto, Norman R. Farnsworth, Thawatchai Santisuk, Vichai Reutrakul Revision of the NMR assignments of pterostlbene and of dihydrodehydrodiconiferyl alcohol: Cytotoxic constituents from anogeissus acuminata. Natural Product Letters. Vol.4, No.4 (1994), 267-272. doi:10.1080/10575639408043917 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/9508
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Title
Revision of the NMR assignments of pterostlbene and of dihydrodehydrodiconiferyl alcohol: Cytotoxic constituents from anogeissus acuminata
Abstract
Further phytochemical work on Anogeissus acuminata var. lanceolata (Combretaceae) led to the isolation of pterostiibene (1), dihydrodehydrodiconifery! alcohol (2), and conocarpan (3). The structure of these compounds were determined by spectroscopic means, mainly through ID and 2D NMR experiments. A revision of some of the 13 C NMR chemical shifts of 1 and 2 were made possible by HETCOR, FLOCK, and selective INEPT experiments. Homonuclear spin-decoupling and 'H^H COSY experiments also enabled the precise assignment of the 'H NMR chemical shifts of 2. Compounds 1–3 exhibited in vitro cytotoxicity in various cancer cell lines. This is the first isolation of 1–3 from Anogeissus. © 1994, Taylor & Francis Group, LLC. All rights reserved.