Antimicrobial activity of Thai medical herbal extracts against mutans streptococci and candida albicans in vitro / Go Yoshimura
5
Issued Date
2007
Copyright Date
2007
Resource Type
Language
eng
File Type
application/pdf
No. of Pages/File Size
viii, 55 leaves : ill.
Access Rights
open access
Rights
ผลงานนี้เป็นลิขสิทธิ์ของมหาวิทยาลัยมหิดล ขอสงวนไว้สำหรับเพื่อการศึกษาเท่านั้น ต้องอ้างอิงแหล่งที่มา ห้ามดัดแปลงเนื้อหา และห้ามนำไปใช้เพื่อการค้า
Rights Holder(s)
Mahidol University
Bibliographic Citation
Thesis (M.Sc. (Maxillofacial Prosthetics))--Mahidol University, 2007
Suggested Citation
Yoshimura, Go, 1969- Antimicrobial activity of Thai medical herbal extracts against mutans streptococci and candida albicans in vitro / Go Yoshimura. Thesis (M.Sc. (Maxillofacial Prosthetics))--Mahidol University, 2007. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/96762
Title
Antimicrobial activity of Thai medical herbal extracts against mutans streptococci and candida albicans in vitro / Go Yoshimura
Author(s)
Advisor(s)
Abstract
Head and neck cancer is a potentially life-threatening disease and maxillofacial prosthodontists have important roles in rehabilitation of the patients who were suffered from this cancer. Candida infection is one of the most common and potentially serious complication in patients who are exposed to chemotherapeutic agents and/or radiation. The effect of these conjunctive cancer therapies causes a reduction in saliva flow, and increases in the amount of dental caries and fungal infection which are major complications in this group of patients. Local herbal products in Thailand contains some substances that may have potential benefit in antimicrobial activities. This study focused on antimicrobial activity of herbal essential oils from plants such as plai, mint, guava, hairy basil, clove and lemongrass and the combination of these herbal essential oils against Mutans streptococci and Candida albicans. Six individuals and seven combinations of essential oils were prepared and evaluated for the antimicrobial activity of essential oils by using disk diffusion test and agar dilution test to determine Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). Each individual and combination showed various activities against test microorganisms. Candida albicans exhibited a higher response than Mutans streptococci to each individual oil and combination of essential oils. For MIC and MBC determinations, Clove as single usage and Plai + Mint + Clove + Hairy basil in combination showed the highest antimicrobial activities in tested solutions. Combinations of herbal essential oil showed promising result for antimicrobial activity against Mutans streptococci and Candida albicans. Further study should be conducted in purifying extracts and evaluating an exact amount of concentration in each extract that can inhibit the growth of oral microorganism.
Description
Maxillofacial Prosthetics (Mahidol University 2007)
Degree Name
Master of Science
Degree Level
Master's degree
Degree Department
Faculty of Dentistry
Degree Discipline
Maxillofacial Prosthetics
Degree Grantor(s)
Mahidol University