Generation of a human iPSC cell line (MUSIi017-A) from a donor with O negative blood type
Issued Date
2024-08-01
Resource Type
ISSN
18735061
eISSN
18767753
Scopus ID
2-s2.0-85195319474
Journal Title
Stem Cell Research
Volume
78
Rights Holder(s)
SCOPUS
Bibliographic Citation
Stem Cell Research Vol.78 (2024)
Suggested Citation
Jiamvoraphong N., Lorthongpanich C., Klaihmon P., Kheolamai P., Issaragrisil S. Generation of a human iPSC cell line (MUSIi017-A) from a donor with O negative blood type. Stem Cell Research Vol.78 (2024). doi:10.1016/j.scr.2024.103466 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/98754
Title
Generation of a human iPSC cell line (MUSIi017-A) from a donor with O negative blood type
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Abstract
The Rh-negative type O blood group (O Rh-) is considered a universal donor for emergency blood transfusions. Due to the constant shortage of this rare blood group, the production of blood cells from iPSCs derived from the O Rh- donor could potentially serve as a limitless blood source for transfusions. In this report, we establish a MUSIi017-A iPSC line from peripheral blood mononuclear cells of a healthy donor with the O Rh- blood group. The established iPSC line exhibited a normal karyotype, showed identical STR compared to donor peripheral blood mononuclear cells, and could differentiate to all three germ layers.