Effects of intraocular pressure change on intraocular lens power calculation in primary open-angle glaucoma and ocular hypertension
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Issued Date
2024-01-01
Resource Type
eISSN
19326203
Scopus ID
2-s2.0-85195627742
Pubmed ID
38857282
Journal Title
PloS one
Volume
19
Issue
6
Rights Holder(s)
SCOPUS
Bibliographic Citation
PloS one Vol.19 No.6 (2024) , e0304169
Suggested Citation
Chirapapaisan C., Eiamsamarng A., Chirapapaisan N., Raksong W., Sakiyalak D., Koodkaew S., Subunnasenee A. Effects of intraocular pressure change on intraocular lens power calculation in primary open-angle glaucoma and ocular hypertension. PloS one Vol.19 No.6 (2024) , e0304169. doi:10.1371/journal.pone.0304169 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/98813
Title
Effects of intraocular pressure change on intraocular lens power calculation in primary open-angle glaucoma and ocular hypertension
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Abstract
This study aimed to assess the effect of intraocular pressure (IOP) changes on biometry and intraocular lens (IOL) power calculation in patients diagnosed with primary open-angle glaucoma (POAG) and ocular hypertension (OHT). This prospective non-randomized cohort study enrolled patients with diagnosed POAG and OHT, presenting with IOP levels exceeding 25 mmHg. Thai Clinical Trials Registry number was TCTR20180912007. Optical biometry, encompassing measurements such as corneal thickness (CCT), keratometry, anterior chamber depth (ACD), and axial length, was conducted before and after IOP reduction. The IOL power was also determined using the SRK/T formula. The main outcomes measured were alterations in biometry and IOL power. Correlations between IOP, biometric parameters, and IOL power were analyzed. In total, 28 eyes were included in the study, with a mean patient age of 65.71±10.2 years. After IOP reduction, all biometric parameters, except CCT and ACD, exhibited a decrease without reaching statistical significance (all p>0.05). Meanwhile, IOL power showed a slight increase of 0.214±0.42 diopters (P = 0.035). The correlation between IOP and biometric parameters was found to be weak. However, there was a moderate correlation between IOP and IOL power (r2 = 0.267). Notably, IOL power tended to increase by more than 0.5 diopters when IOP decreased by more than 10 mmHg (p < 0.001). In conclusion, changes in IOP among patients with POAG and OHT do not significantly impact biometry and IOL power calculations. Nonetheless, it may be prudent to consider a slight adjustment in IOL power when IOP is lowered by more than 10 mmHg.