Effect of intraoperative cold solution irrigation to reduce postoperative pain in knee osteoarthritis patients who underwent unilateral primary total knee arthroplasty: a double-blinded randomized controlled trial
Issued Date
2024-12-01
Resource Type
eISSN
14712474
Scopus ID
2-s2.0-85200264556
Journal Title
BMC Musculoskeletal Disorders
Volume
25
Issue
1
Rights Holder(s)
SCOPUS
Bibliographic Citation
BMC Musculoskeletal Disorders Vol.25 No.1 (2024)
Suggested Citation
Charoenwisetsin S., Jiranantarat V., Hirunyachoke P., Udomkiat P. Effect of intraoperative cold solution irrigation to reduce postoperative pain in knee osteoarthritis patients who underwent unilateral primary total knee arthroplasty: a double-blinded randomized controlled trial. BMC Musculoskeletal Disorders Vol.25 No.1 (2024). doi:10.1186/s12891-024-07732-3 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/100387
Title
Effect of intraoperative cold solution irrigation to reduce postoperative pain in knee osteoarthritis patients who underwent unilateral primary total knee arthroplasty: a double-blinded randomized controlled trial
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Abstract
Purpose: To compare the postoperative pain score, opioid consumption, and blood loss in knee osteoarthritis patients who underwent unilateral primary total knee arthroplasty with and without intraoperative cold solution irrigation. Method: In total, 70 knee osteoarthritis patients were randomly included in the study and allocated into 2 groups. The first group was irrigated intraoperatively with a cold solution and the second group was irrigated intraoperatively with a room-temperature solution. Results: The cold solution group showed significantly lower pain scores (numerical rating scale, NRS) at 28 h postoperatively (p = 0.047). There were no significant differences in opioid consumption or blood loss between the groups. Conclusions: Intraoperative cold solution irrigation in unilateral primary total knee arthroplasty patients may provide the benefit of early postoperative pain reduction for up to 28 h but has no effect in terms of reducing opioid consumption or blood loss. Trial registration: The trial was registered in the Thai Clinical Trials Registry (TCTR) Trial registration number ID: TCTR20200706001 on 06/07/2020.