Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital
Issued Date
2024-08-01
Resource Type
ISSN
23318880
eISSN
23318945
Scopus ID
2-s2.0-85200601390
Journal Title
Universal Journal of Public Health
Volume
12
Issue
4
Start Page
650
End Page
659
Rights Holder(s)
SCOPUS
Bibliographic Citation
Universal Journal of Public Health Vol.12 No.4 (2024) , 650-659
Suggested Citation
Tonkulrat W., Chaveepojnkamjorn W., Ekcjariyawat P., Mongkolsomlit S. Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital. Universal Journal of Public Health Vol.12 No.4 (2024) , 650-659. 659. doi:10.13189/ujph.2024.120404 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/100448
Title
Factors Associated with Carbapenem-resistant Klebsiella pneumoniae Infections among Inpatients in a Tertiary Health Care Hospital
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Corresponding Author(s)
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Abstract
Carbapenem-resistant Klebsiella pneumaoniae infections (CRKPIs) are major health problems of drug resistance worldwide. The present study aimed to determine factors associated with CRKPIs among inpatients in a tertiary healthcare hospital. A hospital-based case-control study was based on the medical records of the patients who were infected with K. pneumoniae after being admitted for more than 48 hours in the Nopparat Rajathanee Hospital (NRH) from January 1, 2020 to December 31, 2020. 145 patients with CRKPIs were assigned as cases while 290 patients with carbapenem-susceptible K. pneumoniae infections (CSKPIs) as controls. Descriptive statistics and multivariable logistic regression were used in data analysis. The average age of the study subjects was 69.3 years (SD = 15.6) among cases. The mean length of hospital stay among cases was 22.2 days (SD = 14.9). Multivariable logistic regression showed significant associations with CRKPIs, renal diseases (Adjusted OR = 2.1; 95%CI = 1.1-3.8), previous hospitalizations (Adjusted OR = 2.1; 95%CI = 1.2-3.8), central venous catheterization (CVC) > 7 days (Adjusted OR = 2.7; 95%CI = 1.1-6.8), and urinary catheter > 7 days (Adjusted OR = 2.7; 95%CI = 1.1-6.4). Therefore, it should be a guideline for surveillance of risk factors of CRKPIs among inpatients. Additionally, the results of the study can be used to monitor and assess the risk of CRKPIs to prevent the complications of patients.